Protein Info for ABIE51_RS08280 in Lysobacter sp. OAE881

Annotation: sulfatase-like hydrolase/transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 615 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 47 to 72 (26 residues), see Phobius details amino acids 81 to 99 (19 residues), see Phobius details amino acids 105 to 124 (20 residues), see Phobius details amino acids 134 to 157 (24 residues), see Phobius details amino acids 172 to 190 (19 residues), see Phobius details PF11893: DUF3413" amino acids 13 to 229 (217 residues), 95.8 bits, see alignment E=3.7e-31 PF00884: Sulfatase" amino acids 253 to 531 (279 residues), 117.9 bits, see alignment E=8.5e-38 PF01663: Phosphodiest" amino acids 427 to 480 (54 residues), 25.8 bits, see alignment 1.2e-09

Best Hits

KEGG orthology group: K07014, (no description) (inferred from 52% identity to sml:Smlt3410)

Predicted SEED Role

"Choline-sulfatase (EC 3.1.6.6)" in subsystem Choline Transport or Choline and Betaine Uptake and Betaine Biosynthesis (EC 3.1.6.6)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.6.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (615 amino acids)

>ABIE51_RS08280 sulfatase-like hydrolase/transferase (Lysobacter sp. OAE881)
MEDVAPPLRQRANAWLTGLILGNAVLACLITLSNIPLTDAGSAWHSTLFLLLALPGHFIF
FGAIVALPAYVLGRVVRNPRWMIALAVLMQTGWLLLLLADAKVFALYRFHLNAMVANMIF
GGALQDQVAFSAKMWALIALGAATLLALQVLGARLWWQALRRRPVLLHIRKAWWIAVSLF
LVSQGMAAYSDARGDRAVMSQLTYIPWAQPITLKNALHRFGVQTAQAHELPDAGDRLGYP
RSAPQCAASPSLNVLLVLVESLRHDMLDPAVMPNTWRYAQDAQWFRNHYSTGNATRFGLF
GLMYGLPGGYWQAMLAQQRGPVMIDRMLADRYAMHIYGSAPLYSPEFDRTVFSKVRDRIV
IGPPKAKSAERDRFVVSRMQADIRNHPKGQPFFGFVFLDSPHAPYHLPDGYRSPFQPMAQ
DVNFLNLGPDHDPTPEFNRYRAAVHYSDALIGELLHTLEQSGLAKNTVVLITGDHGEEFN
DMRKNYWGHNGNFSDYQLRTPFVLHWPGRPARRVDAATSHEDFVPTVMRHALGCESDSAD
YSTGMDLFGELPRKRPLLVESWSQRGIRDGALIYLFDNFGSASVVDRNYDAIPDADVSAD
AVRESWEMLTRFQKR