Protein Info for ABIE51_RS07765 in Lysobacter sp. OAE881

Annotation: MATE family efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 488 transmembrane" amino acids 21 to 29 (9 residues), see Phobius details amino acids 60 to 82 (23 residues), see Phobius details amino acids 95 to 117 (23 residues), see Phobius details amino acids 137 to 158 (22 residues), see Phobius details amino acids 170 to 189 (20 residues), see Phobius details amino acids 198 to 219 (22 residues), see Phobius details amino acids 246 to 269 (24 residues), see Phobius details amino acids 288 to 308 (21 residues), see Phobius details amino acids 325 to 345 (21 residues), see Phobius details amino acids 369 to 387 (19 residues), see Phobius details amino acids 393 to 411 (19 residues), see Phobius details amino acids 423 to 443 (21 residues), see Phobius details PF01554: MatE" amino acids 23 to 184 (162 residues), 111 bits, see alignment E=5e-36 amino acids 252 to 412 (161 residues), 97.2 bits, see alignment E=8.3e-32 TIGR00797: MATE efflux family protein" amino acids 23 to 425 (403 residues), 246.9 bits, see alignment E=1.7e-77 PF14667: Polysacc_synt_C" amino acids 137 to 264 (128 residues), 46.4 bits, see alignment E=4.6e-16

Best Hits

Swiss-Prot: 40% identical to YOEA_BACSU: Probable multidrug resistance protein YoeA (yoeA) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 75% identity to sml:Smlt1381)

Predicted SEED Role

"Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM, homolog"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (488 amino acids)

>ABIE51_RS07765 MATE family efflux transporter (Lysobacter sp. OAE881)
MAPTSHNLTEGPIGRNLFAFALPILAGNIAQSLNGSVNAVWVGRFLGEEALTATANANNI
MFFLIGSVFGIGMAATILIAQAMGARDLTQARRVMGTSATFFIGLSIVIAAGGQWFSRHL
LAAMGTPEASLHLAEDYLRVIFLAMPALYAFAFLSAALRGAGDARTPFRFLLVAVLLDIV
LNPVLIFGMGPFPKLGIAGSAWATLVAQTTTLIALLFYLRHKRHVLWLGRQDARYFIIDR
TILRSLIVKGVPMGLQMVLISLAMIAMMTMVNQHGTQTTAAYGAALQLWTYVQMPAMAVG
AACSSMAAQNVGAHRWDRVSATARAGVLMNFLMTGALIVPLIVFDRWTLSLFLPDGSDAL
EVARHLNHIAVWSFLFFGVTFVVSGVVRSTGAVVPPLIILVIALWGIRVPFADFMQPRIG
VDAIWWSFPISALCSMVMALAYYRFGGWRKARMLVPDRHEVAVPAEVPATPPSPVADPSA
EPDDALAR