Protein Info for ABIE51_RS07645 in Lysobacter sp. OAE881

Annotation: murein biosynthesis integral membrane protein MurJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 530 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 87 to 109 (23 residues), see Phobius details amino acids 131 to 149 (19 residues), see Phobius details amino acids 157 to 177 (21 residues), see Phobius details amino acids 183 to 206 (24 residues), see Phobius details amino acids 230 to 257 (28 residues), see Phobius details amino acids 269 to 289 (21 residues), see Phobius details amino acids 310 to 332 (23 residues), see Phobius details amino acids 347 to 373 (27 residues), see Phobius details amino acids 385 to 407 (23 residues), see Phobius details amino acids 427 to 450 (24 residues), see Phobius details amino acids 465 to 487 (23 residues), see Phobius details amino acids 499 to 522 (24 residues), see Phobius details TIGR01695: murein biosynthesis integral membrane protein MurJ" amino acids 2 to 402 (401 residues), 402.5 bits, see alignment E=1.4e-124 PF03023: MurJ" amino acids 26 to 400 (375 residues), 405.7 bits, see alignment E=2.3e-125 PF13440: Polysacc_synt_3" amino acids 137 to 335 (199 residues), 40.7 bits, see alignment E=1.8e-14

Best Hits

KEGG orthology group: K03980, virulence factor (inferred from 78% identity to xal:XALc_0920)

Predicted SEED Role

"Proposed peptidoglycan lipid II flippase MurJ" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (530 amino acids)

>ABIE51_RS07645 murein biosynthesis integral membrane protein MurJ (Lysobacter sp. OAE881)
MLKGLLSFSSMTMVSRVLGLVRDIAINQAFGANAGTDAFWVAFRIPNFMRRLFAEGSFST
AFVPVFTEIKETRPHADLKELVARVSGTLGGILMVLTALGLIFTPQIAAVFSPGSLDNAP
KFGLTVDLLRLTFPFILFVSLTALAGGALNSFHRFGLPAFTPVILNLFMIAGALWLAPHL
EVPILALGWAVLAGGIAQLVFQLPALRKLDLLTLPKWGWRHPDVRKVMRLMVPTLFGSSV
AQINLLLDTVIASLLFVGSQTWLSQADRFLELPLGVFGVALGTVILPALSRHHVKTDTEG
FSKALDWGLRTTLLIAMPAMLGLMFLAEPLVATLFQRGKFTAFDTQMAAMSVFGLSFGLP
AFALVKIVLPAFYARQDTRTPVRAGIASLIANMVLNVLFLWVLYLLWTTPEVRAKGVFAA
LEQTPGLHLALGFASAAASYLNLALLWHWLRKTGVYERQPGWLRYLMRLLVACVAMSAAL
WVGLQWAPAFTQIGQLARVGYLAVLVGGGGMVYLVALLALGFRPRDLREH