Protein Info for ABIE51_RS06610 in Lysobacter sp. OAE881

Annotation: M13 family metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 667 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF05649: Peptidase_M13_N" amino acids 39 to 414 (376 residues), 290.2 bits, see alignment E=3.5e-90 PF01431: Peptidase_M13" amino acids 469 to 662 (194 residues), 148.9 bits, see alignment E=1.6e-47

Best Hits

KEGG orthology group: K07386, putative endopeptidase [EC: 3.4.24.-] (inferred from 63% identity to xca:xccb100_1585)

Predicted SEED Role

"Metallopeptidase"

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (667 amino acids)

>ABIE51_RS06610 M13 family metallopeptidase (Lysobacter sp. OAE881)
MNVRPLACALIACLIAMPHADAQKKRAAKPKAPAAPTACSDFYASANADWLRSNTTPPAS
GSTSALEQLAARSRQQQLDLLDAASKSPQNNVQKLLGDFWASGLDEAAVERDGAQPIAPL
IARIDAVKNAKDIPPSIAALHQVGIPVVFNFGADVDLQDLERHIGYFAQGGLGLPDPAYY
TRNDAETQALMGRYRNYVEKILALTGTPEAQIKTDAQTVLDLETRIATASKSLIDLRDPR
ANFAPVDTKTLAKQYKRLQLGDFLKAQGVTDDRVSMANPQLFTQLDTLVGSLKPAQWKAY
LRWRVGDAMAPYLAKSFRDAEFEFRGRVLRGLAAPQSRPQQVLDAITLAAGPMVGHEYAA
RYYSPATDKRAEDIAKQVREALGQALDRDTRFSAAAKAEAKAKLDRLKIEVGTPNRDLDY
TVQPMGRGSFGSNMLIASTWRHREEMKRIGRGNADRRWDVLPQDPSLAYDITQNRLIVTA
AMLQPPVFDTTKDAAWLYGSYGALVGHELSHGFDNRGRYVDSKQELRDWWTPTETSAWDG
LSKRIAAQYSGFDYPELKGVKVNGAQTADENIADLAGVELAWSAFGSAEPSAAKPAQQSF
YKGWASLWPQRMTEEIARQRAATSVHAPGQWRTNGPLRNQPSFGEANACKAGNAMQLAAD
QQIRLFP