Protein Info for ABIE51_RS06255 in Lysobacter sp. OAE881

Annotation: formimidoylglutamate deiminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02022: formiminoglutamate deiminase
  • amino acids 2 to 446 (445 residues), 570.2 bits, E=1.6e-175
• PF01979: Amidohydro_1
  • amino acids 43 to 409 (367 residues), 110.6 bits, E=5.2e-36

Best Hits

KEGG orthology group: K05603, formimidoylglutamate deiminase [EC: 3.5.3.13] (inferred from 55% identity to rce:RC1_3235)

Predicted SEED Role

"Formiminoglutamic iminohydrolase (EC 3.5.3.13)" in subsystem Histidine Degradation (EC 3.5.3.13)

MetaCyc Pathways

• L-histidine degradation II (5/5 steps found)

KEGG Metabolic Maps

• Histidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.13

Protein Sequence (449 amino acids)

>ABIE51_RS06255 formimidoylglutamate deiminase (Lysobacter sp. OAE881)
MKTLDAEMLWTPDGWHSDAGFDIDDHGRIRARVAAEPTASASWIVPGVANLHSHAFQRAM
AGLAERQTNPSDSFWTWRETMYRFAARFTPDLLRAVATQLYTEMLEAGYTTVCEFHYLHH
APDGRPYDDPAAMSRALIAAARDAGIRLTLLPVLYMTGGFDGRALGERQRRFGHDVDAYL
RLIDTLCEDADPTLHVGCALHSLRAVPPDAMRAVLDALPPSMPVHIHIAEQVGEVQDSLA
LRNARPVEWLLDHASVDARWTLVHATHLTPAETQGIARSGATVAICPTTEANLGDGLFPL
REYLDAGGRWGIGSDSHISVSPVEELRWLEYGQRLFTRHRNIAVRPHSPSVGETLLHDVA
QSARFSSGHAIGTFATGEYADAVVLDTDAPTLFGLTQDDAIDRWIFSGNRPLVRDVYVGG
RRVVENGHHLQRTAISQRYREAMVALMRE