Protein Info for ABIE51_RS05940 in Lysobacter sp. OAE881

Annotation: preprotein translocase subunit SecY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 transmembrane" amino acids 26 to 44 (19 residues), see Phobius details amino acids 80 to 105 (26 residues), see Phobius details amino acids 126 to 146 (21 residues), see Phobius details amino acids 160 to 179 (20 residues), see Phobius details amino acids 191 to 211 (21 residues), see Phobius details amino acids 221 to 242 (22 residues), see Phobius details amino acids 274 to 298 (25 residues), see Phobius details amino acids 323 to 343 (21 residues), see Phobius details amino acids 374 to 396 (23 residues), see Phobius details amino acids 403 to 423 (21 residues), see Phobius details TIGR00967: preprotein translocase, SecY subunit" amino acids 23 to 434 (412 residues), 421.4 bits, see alignment E=1.9e-130 PF00344: SecY" amino acids 79 to 421 (343 residues), 377.2 bits, see alignment E=3.4e-117

Best Hits

Swiss-Prot: 63% identical to SECY_SHIFL: Protein translocase subunit SecY (secY) from Shigella flexneri

KEGG orthology group: K03076, preprotein translocase subunit SecY (inferred from 77% identity to xac:XAC0992)

MetaCyc: 63% identical to Sec translocon subunit SecY (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Preprotein translocase secY subunit (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (454 amino acids)

>ABIE51_RS05940 preprotein translocase subunit SecY (Lysobacter sp. OAE881)
MARSGSNAVAGLGGGLGKFTELRQRLLFVVGALIVYRIGCYIPVPGVNPEAMLRLMETQK
GTIVDMFNMFSGGALHRFSLFALNVMPYISASIIVQLLVQIVPSLKAIQKEGESGRRKIN
QWSRMGAIPLAVFQAWGIATALQAGGASQGIAVVYNPGPGFILTAVIALTAGTMFLMWLG
EQVTERGIGNGVSLIIFAGIVAGLPAAVFGMFEQIRNGDMSALVAIVVVAIVLGFTYFVV
FVERGQRRITVNYARRQGGRSAYMNQSSFLPLKLNMAGVIPAIFASSIVMFPATAANWFS
QGNSGSTLHRVSQWLNPGEPLHMILYAGLIIGFAFFYTALVFNSQETADNLKKSGALIPG
IRPGKATADYIDGVLTRLTAAGAIYLVLVCLLPEVMRTELGTSFYFGGTSLLIVVVVVMD
FIAQIQAHLMSHQYESLLKKANLKGGSRGGLARG