Protein Info for ABIE51_RS05375 in Lysobacter sp. OAE881

Annotation: symmetrical bis(5'-nucleosyl)-tetraphosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00668: bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
  • amino acids 1 to 260 (260 residues), 260.9 bits, E=7.4e-82
• PF00149: Metallophos
  • amino acids 1 to 83 (83 residues), 53.6 bits, E=2.1e-18

Best Hits

Swiss-Prot: 80% identical to APAH_XANCP: Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (apaH) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K01525, bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC: 3.6.1.41] (inferred from 74% identity to smt:Smal_0666)

Predicted SEED Role

"Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41)" (EC 3.6.1.41)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.41

Protein Sequence (336 amino acids)

>ABIE51_RS05375 symmetrical bis(5'-nucleosyl)-tetraphosphatase (Lysobacter sp. OAE881)
MSIWAIGDLQGCYDATQRLLERINFDPARDRLWFCGDLVNRGGQSLETLRLVHSLRDHST
VVLGNHDLSLLAIGERREDEQRKVNPDLQRIVLAEDRDVLLDWLRMQKLVHVDRSLGWMM
VHAALAPQWTTQMAERFAREIEERLHGDQFRRLLKNMYGDKPAWHPKLAGIDRHRAIINV
FTRMRYCTPRGRISFEDKGAPGTQPVGLYPWYEVPGRVERDLKIVCGHWSTLGLFIGHGV
HAIDTGAVWGGKLTALQLDTDELRIVQAPGRDVPAQPPRPRPPHHGGDNRPQRPRPNHNG
QQRRHHARPPHPNGQQGPRNEAQAAAPKATAEQDRD