Protein Info for ABIE51_RS05295 in Lysobacter sp. OAE881

Annotation: response regulator transcription factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 238 PF00072: Response_reg" amino acids 12 to 122 (111 residues), 105.9 bits, see alignment E=1.3e-34 PF00486: Trans_reg_C" amino acids 156 to 229 (74 residues), 64.2 bits, see alignment E=9.9e-22

Best Hits

Swiss-Prot: 40% identical to MPRA_MYCS2: Response regulator MprA (mprA) from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

KEGG orthology group: None (inferred from 88% identity to xal:XALc_2773)

Predicted SEED Role

"Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (238 amino acids)

>ABIE51_RS05295 response regulator transcription factor (Lysobacter sp. OAE881)
MQGTGTRDGGLVLIVEDNRNISEMVGEYLEGRGFEVDYASDGLDGYRLATENNYDVIVLD
LMLPRMDGVELCKKLREEARKSTPVLMLTARDTLDEKLTGLGAGADDYLTKPFAIQELEA
RLRALIRRERRQVGGEVLKVADLVLDPASLRVTRGGSELQLSPIGLRLLTILMRESPRVV
SRQEIEREIWGNGLPDSDTLRSHLYNLRKTIDKPFDKQLLHTVQSAGYRVADISQPPE