Protein Info for ABIE51_RS04590 in Lysobacter sp. OAE881

Annotation: NCS2 family permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 transmembrane" amino acids 24 to 43 (20 residues), see Phobius details amino acids 55 to 76 (22 residues), see Phobius details amino acids 86 to 104 (19 residues), see Phobius details amino acids 110 to 130 (21 residues), see Phobius details amino acids 138 to 157 (20 residues), see Phobius details amino acids 178 to 195 (18 residues), see Phobius details amino acids 201 to 220 (20 residues), see Phobius details amino acids 249 to 272 (24 residues), see Phobius details amino acids 300 to 322 (23 residues), see Phobius details amino acids 334 to 352 (19 residues), see Phobius details amino acids 358 to 377 (20 residues), see Phobius details amino acids 394 to 419 (26 residues), see Phobius details amino acids 429 to 446 (18 residues), see Phobius details PF00860: Xan_ur_permease" amino acids 25 to 407 (383 residues), 177.3 bits, see alignment E=2.1e-56

Best Hits

KEGG orthology group: K06901, putative MFS transporter, AGZA family, xanthine/uracil permease (inferred from 77% identity to smt:Smal_0570)

Predicted SEED Role

"Xanthine/uracil/thiamine/ascorbate permease family protein" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (447 amino acids)

>ABIE51_RS04590 NCS2 family permease (Lysobacter sp. OAE881)
MARPAPRALDSLFRLRQHGTDVRTELVAGLTTFLTMSYIVFVNPSVLGNTGMDTGAVFVA
TCLAAAIGSLVMAFAANYPVGMAPGMGLNAFFAFTVVGAMGYTWQQALGAVFVSGVVFLL
LSITGARAWLIAGIPHSLRSAITAGIGLFLAIIALQKSELIVGDPDTLVALGDLREPEPL
LAVAGFLLIAVLEAWRVRGAILIGILAVTATALVFGRVQYHGIVDLPPSLAATFMQLDIR
GALGGGDGFSIAAMLHVVIVFVLVEVFDATGTLMGVARRAGLLPPDDASAAQQKRFGRAL
FADSTAILAGSVLGTSSTTAYIESASGVQAGGRTGLTALVVAALFLLALLFSPLAGMVPP
YATAPALLFVAGLMLRELGDVHWDDLTEAIPAALCTLAMPFTYSIANGLAFGFIAYAVLK
LFTGRAREVHAAVWLVAALFVVRFALE