Protein Info for ABIE51_RS04145 in Lysobacter sp. OAE881

Annotation: lipid kinase YegS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 TIGR03702: lipid kinase YegS" amino acids 4 to 307 (304 residues), 389.4 bits, see alignment E=8.8e-121 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family" amino acids 5 to 301 (297 residues), 197.1 bits, see alignment E=3.1e-62 PF00781: DAGK_cat" amino acids 5 to 129 (125 residues), 87.3 bits, see alignment E=6.3e-29 PF19279: YegS_C" amino acids 147 to 298 (152 residues), 65.7 bits, see alignment E=4.3e-22

Best Hits

Swiss-Prot: 64% identical to YEGS_STRMK: Probable lipid kinase YegS-like (Smlt4314) from Stenotrophomonas maltophilia (strain K279a)

KEGG orthology group: K07029, (no description) (inferred from 65% identity to psu:Psesu_2502)

Predicted SEED Role

"Transcription regulator [contains diacylglycerol kinase catalytic domain]"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (315 amino acids)

>ABIE51_RS04145 lipid kinase YegS (Lysobacter sp. OAE881)
MATHWRLILNGKSAGNDAVRDAVQAMRAGGATLDVRVTWEHGDAARYVDEAIDDGVHCVI
AGGGDGSLGEVAAALAERHEDATTLPALAAMPLGTANDFATAATIPLDPHDALRLVADTP
AHAIDMLRVEADGVRHWCINLASGGFGTEVTVETDDGLKKLLGGLAYLVTGIAKMGRIEP
VAAHVHGEGLDWRGALIALGVGNGRQAGGGQLLCPDARIDDGLLDVTVIPELEGELATTA
ATLVREGRGAALERVGERARMRAVAIEAEDGEIALNLDGEPVQARRFAIACVPARLRMHL
PEHCPLLAPARLALR