Protein Info for ABIE51_RS03555 in Lysobacter sp. OAE881

Annotation: Xaa-Pro peptidase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 417 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01321: Creatinase_N" amino acids 52 to 187 (136 residues), 66.4 bits, see alignment E=3.7e-22 PF00557: Peptidase_M24" amino acids 195 to 400 (206 residues), 179.5 bits, see alignment E=7.5e-57

Best Hits

KEGG orthology group: K01271, Xaa-Pro dipeptidase [EC: 3.4.13.9] (inferred from 65% identity to aex:Astex_1858)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.9, 3.4.13.9

Use Curated BLAST to search for 3.4.11.9 or 3.4.13.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (417 amino acids)

>ABIE51_RS03555 Xaa-Pro peptidase family protein (Lysobacter sp. OAE881)
MRRRDFLSAAVAASGALMLPGGLALAAPAGVTGLTSLTVGTKPISPEERMARIARLQRLM
VEQEIGALIVESGSSLDYFTGVQWHRSERTTAAVIPARGDVIIVTPAFEEPSIRETLAVS
GDVRPWNEHESPFDLIVGALRDRGVKSGAIAFESTTRLFIVDGVREASAGAYRIVSGDAL
VKAVRLIKSPAELALMQAANNVTLAALRYVHDNVRIGMRPEELGAMIDAATAALGGEPGF
ALVLLNEASAYPHGSKQPQTVREGSVILMDVGCTLHGYQSDISRTWVMGKPTAKQRKVWD
TVKRGQELALATAKPGVPVGAIDDAVRAMYEKEGWGPGYRLPGLSHRTGHGIGLDGHEPP
YLVHGDTTPLAPGMCFSDEPGLYIPGEFGIRMEDCWYMTESGPKLFTQLAKSIDDPI