Protein Info for ABIE51_RS02935 in Lysobacter sp. OAE881
Annotation: TolC family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 68% identity to sml:Smlt2459)Predicted SEED Role
"Heavy metal RND efflux outer membrane protein, CzcC family" in subsystem Cobalt-zinc-cadmium resistance
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (425 amino acids)
>ABIE51_RS02935 TolC family protein (Lysobacter sp. OAE881) MFSRLAASAALVVVLVAALPARAGDRLTLDDAFARVAASHPDLRLPALRGEILAAELDEA LQRPALRAGVELENAPGTGDYSGVDGAELTLSLASVLERGGKRDARRALAQGRIDALAPE REAARLDLLAETARRYLDVVGAKHRRDLADADIAQRTRTVAAARHRFQAGASPESVLLTA QAALARAQLEQRRAAQTMDAARQHLAALWGEREPRFETTDIDPLALPAIADFDALAATLE RTPELARFANERRIGEARLQLARSQAKADIDWQLGVRAFNDTDDAALVASASMPLGGTRR AQPQIRAAEAGLAMLEVERESRGISLYSTLVDAHGRYRVAQLEVLRLRDDVLPTLVRAEA AAERAYRAGAISYLEWAQLQSERTALARQQLDTALDAHRALIEIQRLTGDALVQPTARTE QEPTP