Protein Info for ABIE51_RS02520 in Lysobacter sp. OAE881
Annotation: cyclopropane-fatty-acyl-phospholipid synthase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00574, cyclopropane-fatty-acyl-phospholipid synthase [EC: 2.1.1.79] (inferred from 62% identity to smt:Smal_1954)Predicted SEED Role
"S-adenosyl-L-methionine dependent methyltransferase, similar to cyclopropane-fatty-acyl-phospholipid synthase"
MetaCyc Pathways
- cis-cyclopropane fatty acid (CFA) biosynthesis (1/1 steps found)
- sterculate biosynthesis (1/2 steps found)
- mycolate biosynthesis (25/205 steps found)
- superpathway of mycolate biosynthesis (26/239 steps found)
Isozymes
Compare fitness of predicted isozymes for: 2.1.1.79
Use Curated BLAST to search for 2.1.1.79
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (423 amino acids)
>ABIE51_RS02520 cyclopropane-fatty-acyl-phospholipid synthase family protein (Lysobacter sp. OAE881) MSDTARQTLSLPDAGVVDRLLRDRVVSQLRALRSGAVTLRDPWGSAALGEHAGRAPSPTL RVNDARFYRAVALGGSVGAAEAYMDGAWACDDLVGLVRLLVRNRDLLDDVERGPARVAGW ALRAAHALRRNTASGARRNIAAHYDLGNTFFRLFLSDDLMYSSALFEREDDTLEDASTRK LQAICRKLDLREGERVLEIGTGWGGFALHAAREHGCHVTTTTLSREQYELACQRVAEAGL QDRVTVLMRDFRELDGTYDKLASIEMVEAIGPENLRRYFACIGERLADHGLALVQAITIE DHRYEQAVRSVDFIKRHVFPGSFIPSIAAMMSAKTAASDLALLHLEDMGLSYARTLQTWR ERFLDRLPEVRALGFDERFIRMWEFYLAYCEGGFRERSIGVAQMLFARPGFRPRAQAAVV SET