Protein Info for ABIE51_RS02120 in Lysobacter sp. OAE881

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 transmembrane" amino acids 24 to 41 (18 residues), see Phobius details amino acids 57 to 79 (23 residues), see Phobius details amino acids 86 to 105 (20 residues), see Phobius details amino acids 111 to 134 (24 residues), see Phobius details amino acids 155 to 176 (22 residues), see Phobius details amino acids 188 to 207 (20 residues), see Phobius details amino acids 241 to 259 (19 residues), see Phobius details amino acids 278 to 298 (21 residues), see Phobius details amino acids 307 to 329 (23 residues), see Phobius details amino acids 335 to 356 (22 residues), see Phobius details amino acids 368 to 389 (22 residues), see Phobius details amino acids 400 to 419 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 20 to 235 (216 residues), 106.8 bits, see alignment E=2e-34 amino acids 228 to 424 (197 residues), 33.7 bits, see alignment E=2.9e-12 PF07690: MFS_1" amino acids 29 to 372 (344 residues), 88.1 bits, see alignment E=8.3e-29 amino acids 246 to 423 (178 residues), 37.6 bits, see alignment E=2e-13

Best Hits

Swiss-Prot: 55% identical to KGTP_ECOLI: Alpha-ketoglutarate permease (kgtP) from Escherichia coli (strain K12)

KEGG orthology group: K03761, MFS transporter, MHS family, alpha-ketoglutarate permease (inferred from 71% identity to pap:PSPA7_6332)

MetaCyc: 55% identical to alpha-ketoglutarate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-23

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>ABIE51_RS02120 MFS transporter (Lysobacter sp. OAE881)
MDATAPMTPTQRLRSIFSGSVGNLVEWYDWYAYSAFAIYFAPHFFPKGDTTAQLLDTAAV
FAVGFLMRPVGGWLMGLYADRHGRKAALMLSVLLMCAGSLLIAVAPGYERIGIAAPALLV
FARLLQGLSVGGEYGTSATYLSEMAQSKHRGFWSSFQYVTLVMGQLLALALLVLLQRALL
TEEQLHDWGWRIPFVVGALCAVTALWLRRGMQETESFAAARTRDTKQRGSLRVLMQHPRE
VLTVIGLTMGGTLSFYTFTTYPQKFLVNTGGFSKADATLISAVSLFVFMLLQPIVGALSD
RTGRRPILIAFGVLGTLFTYTILSGIAASRTVMDAFVWVMSGLLIVSGYTSINAVVKAEL
FPAHIRALGVGLPYALTVSVFGGTAEYIALWFKQIGHESWFYVYVTACVAVSLGVYALMR
DTKLHSRIDRDHDIPNAGEHA