Protein Info for ABIE51_RS01570 in Lysobacter sp. OAE881
Annotation: family 20 glycosylhydrolase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)
MetaCyc Pathways
- chitin degradation II (Vibrio) (3/6 steps found)
- chitin degradation III (Serratia) (3/7 steps found)
- peptidoglycan recycling I (8/14 steps found)
- peptidoglycan recycling II (3/10 steps found)
KEGG Metabolic Maps
- Aminosugars metabolism
- Glycosaminoglycan degradation
- Glycosphingolipid biosynthesis - ganglio series
- Glycosphingolipid biosynthesis - globo series
- Nucleotide sugars metabolism
- Other glycan degradation
Isozymes
Compare fitness of predicted isozymes for: 3.2.1.52
Use Curated BLAST to search for 3.2.1.52
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (994 amino acids)
>ABIE51_RS01570 family 20 glycosylhydrolase (Lysobacter sp. OAE881) MRRHFVTSIAAVALAMGLSACQREDAPKADAAGNAAAKPAEQTTATTLISASAAATPVIP RPAKVELRDGRFAFGPQSRVAVIGNDAEATRIAQDFASRVQKARGFAPQVGGAADGAAVV FAIDANIAPAGDEAYVVDITPQGARISARKPAGLFYGAVTLWQLLADGAQGEASVATQRI EDAPRFGWRGLMLDVARHFRTPDEVKALLDQMALHKLNTFHWHLTDDQGWRVEIKRYPKL TEVGGCRIPAGAAGRDAKGKPKPYCGFYTQDEIRDIVKYAAERYITVVPEFDLPGHAQAA IASYPEFGVPGTKPPVSPDWGVNTWLFNVDDKTFTFLENVLDEMMPLFPGQYFHLGGDEA AKDQWEQSAAVQAKKKELGLKDEMQLQSWFMGRLGKYIEAHGKRLIGWDEILEGGPPADA TVMSWRGTDGAIEAARAGHDVVMAPSPDLYLDHVQSDGPDETPGRLKVISLKDVYDFKAV PVQLNADQARHVLGVQANLWTEHQRTFERMQRSLFPRGAALAEVTWSPESRLDWNDFLQR MAFQMERYRLTGFDAADSAFAVRFTPQALEDGKTSLALNNQSGFGTIRYTLDGTEPTATS QAYVHPLELPLPTTVKANAFADDRALAATRAFELDLHSLRARSSNALRSCKTDLMLRMED DAPSDGKDGDRRLLLADVFDPCWIYDAAQLDGIATVEVRVGQLPHNYALWKDASKVVTRP AKIPGGALEVRLGSCEGEPIAVLPLAPARKSDGLTTLSTPLPTQAGRHDLCFTFASGRVQ PDVGRGRGRAAARGALSEAMKPLSRPRERGGPGRRPSHLAEMALRLALALPITRSGTPER RDPGPVRVRIAALHRGIHTCLVALFSRRPFWPSPAPCRRKTCRVRRSSTSTPTPTPSDRS SPCAKPATPPPRNWSRPSSAIRARRAKSPSSRTWRWPPAARTSASSSIRARSVRSIAATR CGARSCGITAGTCIAPAISTAHSRSGARWSKRVR