Protein Info for ABIE51_RS01155 in Lysobacter sp. OAE881

Annotation: pimeloyl-ACP methyl ester esterase BioH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 257 TIGR01738: pimelyl-[acyl-carrier protein] methyl ester esterase" amino acids 7 to 249 (243 residues), 267 bits, see alignment E=8.3e-84 PF00561: Abhydrolase_1" amino acids 10 to 236 (227 residues), 86 bits, see alignment E=5e-28 PF12146: Hydrolase_4" amino acids 12 to 214 (203 residues), 43.2 bits, see alignment E=4.5e-15 PF12697: Abhydrolase_6" amino acids 14 to 244 (231 residues), 82.8 bits, see alignment E=8.7e-27

Best Hits

Swiss-Prot: 58% identical to BIOH_XANOR: Pimeloyl-[acyl-carrier protein] methyl ester esterase (bioH) from Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)

KEGG orthology group: K02170, biotin biosynthesis protein BioH (inferred from 58% identity to xom:XOO_0215)

Predicted SEED Role

"Biotin synthesis protein BioH"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (257 amino acids)

>ABIE51_RS01155 pimeloyl-ACP methyl ester esterase BioH (Lysobacter sp. OAE881)
MYIETRGQGPALALIHGWAMHGGLFAPLVERLQDRYTLHLIDLPGHGRAREDATPLSPEA
LAPQLIARVPDAVWLGWSLGGQFALRAALDFPEDVRGLVMIASSPRFVIDEGWPHGVKPS
LFRDFGEALGRDFRGTLEGFLALEALGSSYAQEELRSLKAQAFERGEPAPRALQEGLVLL
DRLDLRDELPQLRVPSLWISGRRDRLIPAGAMPAAAAMTPGARSVVIGNAGHAPFLGAAD
EVAAEIDAFMRAVTAPA