Protein Info for ABIE51_RS00725 in Lysobacter sp. OAE881

Annotation: energy transducer TonB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF03544: TonB_C" amino acids 273 to 344 (72 residues), 71.2 bits, see alignment E=4.1e-24 TIGR01352: TonB family C-terminal domain" amino acids 275 to 346 (72 residues), 71.3 bits, see alignment E=3.3e-24

Best Hits

KEGG orthology group: K03832, periplasmic protein TonB (inferred from 53% identity to xca:xccb100_4157)

Predicted SEED Role

"Ferric siderophore transport system, periplasmic binding protein TonB" in subsystem Campylobacter Iron Metabolism or Hemin transport system or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (348 amino acids)

>ABIE51_RS00725 energy transducer TonB (Lysobacter sp. OAE881)
MTFVNPQDRRSRRLSVVSQLSVALALCCALAACNKEEPAQPTAAAPAATQSAPAVTAETA
VSAKVSALTADQLREAARKAYAENRLYAPAEDNAVEYYLALRDKAPGDAAVSSALTDLLP
MTVIATEQSVNREDFVEAQRLAALLEKADAQHPALARLKASIAAQQDASTKRAAQQQLTA
EEEAKKKVELEKKRVEDQKKQQEDAARQLAAQQAATKQADDKAAADKAAADKAAADQRAA
DARAAEQRAAAARQAAAAPASADASDLRPLSMPPPRYPPEALRAGTSGEVQVEFTVGTDG
SVTAARVVRSNPARIFDREAVNAVRKWRFQPIDSPVTTRRTIGFNPQS