Protein Info for ABIE51_RS00605 in Lysobacter sp. OAE881

Annotation: LysR substrate-binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF00126: HTH_1" amino acids 7 to 65 (59 residues), 65.8 bits, see alignment E=2.8e-22 PF03466: LysR_substrate" amino acids 93 to 287 (195 residues), 109.5 bits, see alignment E=1.6e-35

Best Hits

KEGG orthology group: None (inferred from 57% identity to smt:Smal_3637)

Predicted SEED Role

"Glycine cleavage system transcriptional activator GcvA" in subsystem Glycine cleavage system or Orphan regulatory proteins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (324 amino acids)

>ABIE51_RS00605 LysR substrate-binding domain-containing protein (Lysobacter sp. OAE881)
MSRPPLQALLGFIAAARAGNLTRAAESMHLTVSALSHQIRTIEERLDRRLFVRGARGVKL
TEHGQALYDRIAPHLEAIELALAPRRVRRDDALAVTLMPSFASSWLVPRLPRFLSAHPQL
EISLQSNIDPIDFSRETAIDAGIRFGPGKWPGVEAVHLFDDWMTPTASPALIERLGRPTL
ATLSQFPLLGAPGGRWSEWFAKFGGKPPERFVAIFDDSENLHRAAAEGMGIVLGRVTLAR
PLVEAGHLVELFDERLKTEFAHYLVYPSRSRDHRGLARFRDWLLEEAATYAASDAMTPRR
GGAPKKAPAKARKPAPAKRTRAVR