Protein Info for ABIE51_RS00295 in Lysobacter sp. OAE881

Annotation: M20 family metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details TIGR01891: amidohydrolase" amino acids 41 to 419 (379 residues), 338.1 bits, see alignment E=3.5e-105 PF01546: Peptidase_M20" amino acids 98 to 427 (330 residues), 137.9 bits, see alignment E=4.4e-44 PF07687: M20_dimer" amino acids 227 to 321 (95 residues), 39.7 bits, see alignment E=4.1e-14

Best Hits

KEGG orthology group: None (inferred from 73% identity to psu:Psesu_0398)

Predicted SEED Role

"N-acetyl-L,L-diaminopimelate deacetylase (EC 3.5.1.47)" in subsystem Lysine Biosynthesis DAP Pathway (EC 3.5.1.47)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.47

Use Curated BLAST to search for 3.5.1.47

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (434 amino acids)

>ABIE51_RS00295 M20 family metallopeptidase (Lysobacter sp. OAE881)
MRPNLLALLTASLLAAPAFAQSTQAPPDTAAAAQAVQKDVVAWRRDIHQHPELGNNEVRT
AKLVADQLRKLGLQVKTGIAHTGVVAVLKGGKPGPRIALRADMDALPVTEQTGLPFASKV
RTTYRGQDVGVMHACGHDAHVAILLGVATALAAQKATLPGEVMFVFQPSEEGPPNAGETF
GAKLMLDEGVFRDFKPDAVFGLHVWAGLPVGQVGVRSGPMLAAADEWSLTVRGAQTHGSR
PWDGVDPITVAAQILLGTQSVIARQVNVAASPAVLTAGQFNAGVRFNIIPDEAKLVGTLR
TFDAAQREDIIARFRRTAEDFAHASGATATLDVAANAPATVNDPALTTRVRPSLQRAVGE
ANVVEMPLQTVAEDFAQFANVVPGVYFFVGSTAKGTDPAKAPINHSPQFLLDEGALDVGV
RSMLQVALDYLGAK