Protein Info for ABIE51_RS00275 in Lysobacter sp. OAE881

Annotation: pitrilysin family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 951 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF00675: Peptidase_M16" amino acids 53 to 192 (140 residues), 59.5 bits, see alignment E=3.9e-20 amino acids 521 to 634 (114 residues), 26.6 bits, see alignment E=5.2e-10 PF05193: Peptidase_M16_C" amino acids 211 to 385 (175 residues), 122.9 bits, see alignment E=1.5e-39 amino acids 674 to 854 (181 residues), 116.1 bits, see alignment E=1.7e-37

Best Hits

KEGG orthology group: None (inferred from 71% identity to psu:Psesu_0119)

Predicted SEED Role

"Zinc protease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (951 amino acids)

>ABIE51_RS00275 pitrilysin family protein (Lysobacter sp. OAE881)
MSASSRPRLAALALALAATFGGVAALTPVAAMAAAKTTVDIPFEEFTLPNGLRVVVHTDR
KAPIVAVNLWYHVGSKDEPAGRTGFAHLFEHLMFNGSENHRGEYFEPFELVGATDMNGTT
NSDRTNYFQNVPTTALDMALWMESDRMGHLLGAIDQKTLDEQRGVVQNEKREGENQPYGQ
VWDALGKALYPKTHPYHHSTIGSMADLDAASLDDVKGWFRTWYGPNNAVLVLAGDIDVAT
AKEKVTKYFGDIPATPTMAQPQVDVAPLAKSTRSTMTDKVPQARVHRVWNVAQAGTPDLD
KLQLFAQVLGGSKSSRLDKRLLHEEKLVDNVSAAAYSMQLSSNFVITADVKQGVDPAKVE
AIIDEELQKLLKDGPTKAELEQARTVFKAGFVRGIERIGGSGGKADALAECTVYTGDPGC
FRDSLKIIDTASARDLTAVANNWLTKGSHTLVVVPGDRTLVAEDPSVTPAPMKLPAVDPR
FTTTASTVDRSAGPPKTSQFPDLRFPSLQRATLKNGTTVILAERHDVPVVQMSYEFAGGF
SADQGRKLGTSSFAMGMMDEGAGELDSLAFGDAAESLGANLGAGASLDGGKAYLSALKQN
LDPSVALFAKMLREPRFDQKEIDRVKASWVAGIKQEKARPNGAAMRVLPPLLYGAGHAYA
IPFSGSGTEASIASLTRDDLLAFHRDWVRPDGATLIVVGDTTLKEIVPLLDKHLGDWKPA
GNAPARPQIGEVARPAKPRVYLIDQPGAVQANIFAGEVVPSTKDADSVRFDIANSVLGGE
FSSRLNMNLRENKHWAYGAYSFSANALGQRPWMAFAPVQIDKTADSLKELNREITDYATG
KAPPKPEEVAKIQATEILSLPGAFETASSVMGAISGIVRYDRPDDYVFKRKAQIEALTPE
QVKAAAATIDPNALTWVVVGDLKQIEKPVRALKLGDVQVLDADGNAVTGTP