Protein Info for ABCV34_RS15580 in Castellaniella sp019104865 MT123

Annotation: polyphosphate kinase 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 689 TIGR03705: polyphosphate kinase 1" amino acids 10 to 686 (677 residues), 910.8 bits, see alignment E=2.7e-278 PF13089: PP_kinase_N" amino acids 11 to 115 (105 residues), 112.9 bits, see alignment E=2.2e-36 PF02503: PP_kinase" amino acids 125 to 307 (183 residues), 193.4 bits, see alignment E=7.5e-61 PF17941: PP_kinase_C_1" amino acids 339 to 500 (162 residues), 238.9 bits, see alignment E=5.9e-75 PF13090: PP_kinase_C" amino acids 510 to 674 (165 residues), 205.4 bits, see alignment E=1.1e-64

Best Hits

Swiss-Prot: 52% identical to PPK1_PSEAE: Polyphosphate kinase (ppk) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K00937, polyphosphate kinase [EC: 2.7.4.1] (inferred from 75% identity to put:PT7_0116)

Predicted SEED Role

"Polyphosphate kinase (EC 2.7.4.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism or Purine conversions (EC 2.7.4.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.4.1

Use Curated BLAST to search for 2.7.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (689 amino acids)

>ABCV34_RS15580 polyphosphate kinase 1 (Castellaniella sp019104865 MT123)
MRGAEETPTLLNRELSVLKFNERVLSMAERPDVPVLERLRYLCIVGSNLDEFFEIRMASL
KEQQRQTPELRSADGMTPGEAFDRVQRAAHVLVDRQNRLLTGEVMPRLMEVGVGLIYSTG
WTDLQREWAYGVFLRDVMPLLTPIGLDPAHPFPRVYNKSLNFIVSLSGEDAFGREGHIAI
VQAPRALPRMVKVPPEISGIPDGFMLLTTLINAFVGDLFPGMNVQGCYQWRVTRNSDLFV
DEEEITNLRQALQGELSQRNFGASVRLEIAHALPPDLELFLQREFNLGPADTYRVNGPVN
LTRLMQLCNRVSRPDLEYPVFRPRIPAPFDGDMQRPETLFAAIAARDHLLHHPYQSFQPV
LMFLQAAALDPQVVAIKQTIYRTGEDSELMGLLLSAARAGKEVTVVVELMARFDEQTNIN
WAARLEEVGAHVSYGVVGHKTHAKMALVLRREDGRIRRYGHLGTGNYHQRTAKLYTDFGL
LTANQAICEDMDQVFSLLTGLGARRELKLLLQSPFTLHETVLNLIRSETEFARAGKRARI
RAKMNSLLEPTVIKALYAASQAGVRIDLIVRGACALQAGVPGLSENIQVRSIIGRFLEHS
RVFYFYQDGAEPLYLSSADWMDRNFLRRVELAFPVLDKTLRRRVIDESFTFAWRDNQLAW
AAQPDGRYQRVRNRRPAFNLHQYLMARLG