Protein Info for ABCV34_RS15325 in Castellaniella sp019104865 MT123

Annotation: apolipoprotein N-acyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 546 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 36 to 54 (19 residues), see Phobius details amino acids 62 to 82 (21 residues), see Phobius details amino acids 94 to 122 (29 residues), see Phobius details amino acids 135 to 155 (21 residues), see Phobius details amino acids 174 to 199 (26 residues), see Phobius details amino acids 211 to 231 (21 residues), see Phobius details amino acids 514 to 533 (20 residues), see Phobius details PF20154: LNT_N" amino acids 19 to 194 (176 residues), 96 bits, see alignment E=2.8e-31 TIGR00546: apolipoprotein N-acyltransferase" amino acids 68 to 486 (419 residues), 290.1 bits, see alignment E=1.5e-90 PF00795: CN_hydrolase" amino acids 284 to 504 (221 residues), 82.9 bits, see alignment E=2.5e-27

Best Hits

KEGG orthology group: K03820, apolipoprotein N-acyltransferase [EC: 2.3.1.-] (inferred from 59% identity to put:PT7_2079)

Predicted SEED Role

"Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE" in subsystem Phosphate metabolism or Copper homeostasis: copper tolerance (EC 2.3.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.-

Use Curated BLAST to search for 2.3.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (546 amino acids)

>ABCV34_RS15325 apolipoprotein N-acyltransferase (Castellaniella sp019104865 MT123)
MASPGRRRGVPIWLRVLLAGAIQALCFAPGPLPAWSLPFVQIASLSVLAAHTWGARGPRQ
AAGYGWLFGLAQFSVGVYWLTISMHEFGGLALPLSIAALLLFAAAMALYAAGACALTAWL
CAAHKNPEQPAWRQILNAAAWAGAWTLFEWLRGTLFTGFTWLNIGYAHAEGMFAAWAPFI
GVYGLAWLSAFAAGAIALMARAKDTTHDRSAAAVIALALASGLLGIAWAHIQWTRPVGDP
LLVRLVQPATPQSDKFDPARFLTAQERTLRLAGLPPKGPDDRPDLIVLPETVLPILQDQV
PDPIWQSWLALADRMNAALVLGLPLHTRTTTGDRYTNGATVIHPGDTQPPLVPGHWHYDK
HHLVPFGEFIPPGFHWFVRALKIPLGDFNRGPLRQPPLLLDGQALAVDICYEDTFGEEIA
ASVRPDDTGAPGASILVNLSNLAWFGNTWALRQHLWIARMRALETARPVIRSTNTGMTAA
IDPTGEVRGMLDPAVPGVLDVEVQGTQGLTPYVRWGNGPILGWALLGLLLAARYRGKTTR
EGRAAS