Protein Info for ABCV34_RS13305 in Castellaniella sp019104865 MT123

Annotation: lipopolysaccharide heptosyltransferase I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 TIGR02193: lipopolysaccharide heptosyltransferase I" amino acids 4 to 314 (311 residues), 372.4 bits, see alignment E=9.6e-116 PF01075: Glyco_transf_9" amino acids 78 to 304 (227 residues), 192 bits, see alignment E=5.7e-61

Best Hits

KEGG orthology group: K02841, heptosyltransferase I [EC: 2.4.-.-] (inferred from 72% identity to put:PT7_3238)

Predicted SEED Role

"Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-)" in subsystem LOS core oligosaccharide biosynthesis (EC 2.4.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.-.-, 2.4.1.-

Use Curated BLAST to search for 2.4.-.- or 2.4.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>ABCV34_RS13305 lipopolysaccharide heptosyltransferase I (Castellaniella sp019104865 MT123)
MSTRILIVRTSSLGDLVHMLPAMSDIARHVPDARIDWIAEEAFAEIPSWHPAVREVIPVA
HRRWRKHWWDARTRRERAALRDMLASREYDVILDMQALLKSVWLVRQARGQRHGLDWKSA
REPLASLFYDVKHRVEFWQPAIIRQRTLAAATFGYSFDGPPDFGLQGLTDGVPIDRVALI
MPSASRDDKLWPAAYWRQVFDHLQAQGLGLRLLAGNETEQARARELIQGRDDAQVLPRLG
LRQVADQLARARLMVGLDSGLTHLSAGLGRPTIGIYKASTPVRTPLQGAAYTASLGERGQ
EPDAGQVMAAIDEALDAARSPMSQPA