Protein Info for ABCV34_RS11725 in Castellaniella sp019104865 MT123

Annotation: tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 638 transmembrane" amino acids 610 to 628 (19 residues), see Phobius details TIGR00136: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA" amino acids 7 to 630 (624 residues), 863.5 bits, see alignment E=4.2e-264 PF12831: FAD_oxidored" amino acids 8 to 152 (145 residues), 37.5 bits, see alignment E=4.7e-13 PF00890: FAD_binding_2" amino acids 8 to 38 (31 residues), 21 bits, see alignment (E = 4.3e-08) PF01134: GIDA" amino acids 8 to 402 (395 residues), 552.4 bits, see alignment E=1.6e-169 PF21680: GIDA_C_1st" amino acids 465 to 565 (101 residues), 70.1 bits, see alignment E=5.7e-23 PF13932: GIDA_C" amino acids 569 to 625 (57 residues), 82.6 bits, see alignment 3.4e-27

Best Hits

Swiss-Prot: 74% identical to MNMG_BORBR: tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG (mnmG) from Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)

KEGG orthology group: K03495, glucose inhibited division protein A (inferred from 76% identity to put:PT7_2920)

Predicted SEED Role

"tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (638 amino acids)

>ABCV34_RS11725 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG (Castellaniella sp019104865 MT123)
MNYTDEFDVLVIGGGHAGTEAALAAARMGASTLLLTHNMDTLGQMSCNPSIGGIGKGHLV
KEVDALGGAMAWATDHAGIQFRILNRSKGPAVRATRAQADRSLYRRAIRMILQEQKNLLI
FQQAVEDLILDGDLVVGAKTQIGLVFRAKTVVLTAGTFLNGLMHVGLSHYAAGRAGDPPA
TSLGQRLKELNLPQGRLKTGTPPRIDAKSIDFSKTEVQPGDLDPVPVFSFLGRADMHPGQ
VPCWITHTTERSHDIVRSGLDRSPLYSDEGTIEGVGPRYCPSIEDKIHRFADKTSHQVFL
EPEGASSCEIYPNGISTSLPFDIQFALVRSLPGLENARIMRPGYAIEYDYFDPRHLHAWL
ETKSIHGLFFAGQINGTTGYEEAAAQGLLAGANAALRVQGKEPWIVPRQDAYLGVLVDDL
VTKGVTEPYRMFTSRAEYRLSLREDNADQRLTDIGRALGLVDDIRWDAFSRKRDAVATEI
QRLQETRINPAVLGAHDRELLALQHQDRHPSLLDLLKRPDVGYEQLMRLQDAQGSLLAGP
GLVEADRVEQLGIQVKYAGYVERQRLEIERQRAQEGQSIPDDFDYTEIPGLSAEVRQRLG
AARPATVGQAGRISGITPAAISLLLVHLKRVQRGRRTA