Protein Info for ABCV34_RS11330 in Castellaniella sp019104865 MT123

Annotation: preprotein translocase subunit SecY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 72 to 96 (25 residues), see Phobius details amino acids 116 to 136 (21 residues), see Phobius details amino acids 148 to 168 (21 residues), see Phobius details amino acids 180 to 197 (18 residues), see Phobius details amino acids 209 to 230 (22 residues), see Phobius details amino acids 268 to 289 (22 residues), see Phobius details amino acids 310 to 331 (22 residues), see Phobius details amino acids 364 to 385 (22 residues), see Phobius details amino acids 391 to 412 (22 residues), see Phobius details TIGR00967: preprotein translocase, SecY subunit" amino acids 17 to 423 (407 residues), 443.6 bits, see alignment E=3.3e-137 PF00344: SecY" amino acids 73 to 411 (339 residues), 398.6 bits, see alignment E=1e-123

Best Hits

Swiss-Prot: 65% identical to SECY_ECOLI: Protein translocase subunit SecY (secY) from Escherichia coli (strain K12)

KEGG orthology group: K03076, preprotein translocase subunit SecY (inferred from 88% identity to put:PT7_2871)

MetaCyc: 65% identical to Sec translocon subunit SecY (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Preprotein translocase secY subunit (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (440 amino acids)

>ABCV34_RS11330 preprotein translocase subunit SecY (Castellaniella sp019104865 MT123)
MAKAQANKPSAGYGDLKRRILFLVLALIVYRMGTHIPVPGINPDALSQLFQQNQGGILGL
FNMFSGGALERFSVLALGIMPYISAAIIMQLLAVVVPSLEAIKKEGQSGQRKITQYTRYG
TVFLALFQAVGISVALESQPGLVIDPGLLFRFTTIVTLVTGSMFLMWLGEQITERGLGNG
ISLLIFAGIVAGLPNALGGMLDLVRTDSMSILSVLFILAVVVAVTYFVVYVERGQRRITV
NYAKRQVGNKLYGGQSSHLPLKLNMSGVIPPIFASSIILLPATVTSWFASNPNMRWLGDL
AAALSPRQPLYVTLYSGLIIFFCFFYTALVFNSRETADNLKKSGAFVPGIRPGEQTARYI
DKILMRLTLSGAVYITLVCLLPELMQMRWNVPFYFGGTSLLIIVVVAMDFMAQAQAYMMS
QQYDSLLRKANFKGAGLPMR