Protein Info for ABCV34_RS11280 in Castellaniella sp019104865 MT123

Annotation: twin-arginine translocase subunit TatC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 271 transmembrane" amino acids 24 to 43 (20 residues), see Phobius details amino acids 81 to 101 (21 residues), see Phobius details amino acids 113 to 140 (28 residues), see Phobius details amino acids 160 to 186 (27 residues), see Phobius details amino acids 198 to 215 (18 residues), see Phobius details amino acids 222 to 242 (21 residues), see Phobius details TIGR00945: twin arginine-targeting protein translocase TatC" amino acids 14 to 232 (219 residues), 221.9 bits, see alignment E=4.5e-70 PF00902: TatC" amino acids 15 to 227 (213 residues), 229.2 bits, see alignment E=2.4e-72

Best Hits

Swiss-Prot: 51% identical to TATC_AZOCH: Sec-independent protein translocase protein TatC (tatC) from Azotobacter chroococcum mcd 1

KEGG orthology group: K03118, sec-independent protein translocase protein TatC (inferred from 78% identity to put:PT7_3111)

MetaCyc: 52% identical to twin arginine protein translocation system - TatC protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-181

Predicted SEED Role

"Twin-arginine translocation protein TatC" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (271 amino acids)

>ABCV34_RS11280 twin-arginine translocase subunit TatC (Castellaniella sp019104865 MT123)
MTDASDASSQDTFISHLIELRTRLLRAVMAVLGIFVVLFLYPGPSTIYDILAQPMLASLP
TGTRMIATGVITPFMVPIKVTLLAAFVLALPVVLYQAWAFVAPGLYRHEQRLALPLIISS
TFLFLLGMAFCYFVVFHTVFRFIANFAPHSITPAPDIEAYVNFVLTMFMAFGVTFEVPVA
VVLLVKTGIVSVKKLREVRGYVVVGAFVLAAVVTPPDVLSQVLLATPLCVLYEIGILAGA
AIEKRKAAPETEDPAADTNALVSQDDPPQDK