Protein Info for ABCV34_RS11150 in Castellaniella sp019104865 MT123
Annotation: glutamate synthase-related protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00265, glutamate synthase (NADPH/NADH) large chain [EC: 1.4.1.13 1.4.1.14] (inferred from 71% identity to aaa:Acav_0979)Predicted SEED Role
"Glutamate synthase [NADPH] large chain (EC 1.4.1.13)" in subsystem Ammonia assimilation or Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis (EC 1.4.1.13)
MetaCyc Pathways
- L-citrulline biosynthesis (7/8 steps found)
- L-asparagine biosynthesis III (tRNA-dependent) (4/4 steps found)
- L-glutamate and L-glutamine biosynthesis (6/7 steps found)
- ammonia assimilation cycle III (3/3 steps found)
- L-glutamate biosynthesis I (2/2 steps found)
- ammonia assimilation cycle I (2/2 steps found)
- superpathway of L-citrulline metabolism (9/12 steps found)
- L-glutamate biosynthesis IV (1/1 steps found)
- L-glutamine degradation I (1/1 steps found)
- L-glutamine degradation II (1/1 steps found)
- glutaminyl-tRNAgln biosynthesis via transamidation (3/4 steps found)
- superpathway of ammonia assimilation (plants) (2/3 steps found)
KEGG Metabolic Maps
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Glutamate metabolism
- Nitrogen metabolism
Isozymes
Compare fitness of predicted isozymes for: 1.4.1.13, 1.4.1.14
Use Curated BLAST to search for 1.4.1.13 or 1.4.1.14
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (1565 amino acids)
>ABCV34_RS11150 glutamate synthase-related protein (Castellaniella sp019104865 MT123) MTQPASCPPGLPAAQGLYHPEYEHDACGVGFVAHIEGNKSHTIIQQALRILENLDHRGAV GADELMGDGAGILLQIPDQLYREEMAAQGVTLPPPDDYGVAMVFLPKETASRLACERELE RAVRDEGQVVLGWRDVPIDHDMKMSPTVRACEPVIRQLFIGRGPDIMVPDALERKLYVIR KTASHAIQRMQLAHGQEYFVPSISVRTVVYKGLLLANQVGVYYRDLADTRAISALALVHQ RFSTNTFPAWPLAHPYRMIAHNGEINTVKGNFNWLRAREGVMTSAVLGEDLGKLYPIVYE GQSDTATFDNCLELLVMSGYSLAHAMMIMIPEAWEQHADMDESRRAFYEYHAAMMEPWDG PAAVAFTDGRQIGATLDRNGLRPARYLITDDKMVILASEAGTLQIPEHRIVKKWRLQPGK MLLIDLQQGRIIDDEEIKSQLANAHPYPQWIQRLRMKLDDLPALKSDDLPEATASLLDRQ QAFGWTQEDFKFILEPMATSGQEAIGSMGNDAPLTVLSDRPKPFYNYFRQMFAQVTNPPI DPIREQLVMSLVSFIGPKPNLLDINNVNPPLRLEISQPVLDQAAMAQLRHISQQTSDKFR CCELDITYPVAWGREGIEACLASLCASAADAVRSGDNILLLSDRKVDADHVAIPALLATS AIHQHLIRAGLRTKTGLIVETGSARETHHFALLGGYGAEAVHPWLALESLTALESSIPHA TENYIKAIGKGLKKVMSKMGISTYMSYTGAQIFEAVGLHNSLVKKYFTGTPSNIEGIDIF QVAEEALRTHQAAFGNSPVLADRLDEGGDYAFRIRGEEHLWTPDSIAKLQHATRANNYST FKEYAQLINDQSKRHMTLRGLFEFRVDPAQAIPLSEVEPAKEIVKRFASGAMSLGSISTE AHATLAVAMNRIGGKSNTGEGGEDALRYRSEMRAGKPTVRKGDTIASVLGKDRVVADIPL AAGDSLRSRIKQVASGRFGVTAEYLCSADQIQIKMAQGAKPGEGGQLPGHKVTDYIAQLR YSVPGVGLISPPPHHDIYSIEDLAQLIHDLKNVNEQASISVKLVAEVGVGTVATGVAKAK ADHVVIAGHDGGTGASPVSSIKHAGIPWELGLSETQQTLVLNRLRSRIRVQADGQMKTGR DVAIAAMLGADEFGFATAPLIVEGCVMMRKCHLNTCPTGVATQDPVLRKKFNGKPEYVVN YFFFVAEEVREIMAQLGIRRVDDLIGRVDLLDMRKGINHWKAHGLDFSRIFHQVQTTDSV HNTDSQDHGLAHALDHQLIDRSKAALERGEKVSFITPVRNRNRTIGAMLSGEVARRYGHE GLPEDTIHIQCNGAAGQSFGAFLAHGITLDLVGEANDYVGKGLSGGRLIVRSPNDFRGFG PDHIIAGNTVLYGATGGEAYFNGVAGERFAVRNSGAVAVVEGTGDHGCEYMTGGTVVVLG ETGRNFAAGMSGGVAYVWDPEHILVRRCNPDMVHLDPMSAHDAQQQAGDKQFWHHQTRDS ERETDETIVRRLVENHFRHTGSFRAREILDDWNQARSAFVKVTPIEYRRALGELWQAAQT RDLAA