Protein Info for ABCV34_RS09495 in Castellaniella sp019104865 MT123

Annotation: peptidylprolyl isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 504 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF09312: SurA_N" amino acids 49 to 160 (112 residues), 104.5 bits, see alignment E=1.2e-33 PF13624: SurA_N_3" amino acids 51 to 160 (110 residues), 47.7 bits, see alignment E=4.9e-16 PF13623: SurA_N_2" amino acids 52 to 128 (77 residues), 41.2 bits, see alignment E=4.7e-14 PF13616: Rotamase_3" amino acids 219 to 316 (98 residues), 44.8 bits, see alignment E=5.2e-15 amino acids 354 to 451 (98 residues), 93.5 bits, see alignment E=4.1e-30 PF00639: Rotamase" amino acids 224 to 316 (93 residues), 52.1 bits, see alignment E=3.3e-17 amino acids 360 to 450 (91 residues), 85.3 bits, see alignment E=1.4e-27 PF13145: Rotamase_2" amino acids 236 to 327 (92 residues), 27.7 bits, see alignment E=1.2e-09 amino acids 386 to 453 (68 residues), 34.7 bits, see alignment E=8.2e-12

Best Hits

Swiss-Prot: 54% identical to SURA_BORA1: Chaperone SurA (surA) from Bordetella avium (strain 197N)

KEGG orthology group: K03771, peptidyl-prolyl cis-trans isomerase SurA [EC: 5.2.1.8] (inferred from 56% identity to put:PT7_0042)

Predicted SEED Role

"Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (504 amino acids)

>ABCV34_RS09495 peptidylprolyl isomerase (Castellaniella sp019104865 MT123)
MMSGLRHPAYVLSLAVALGGSALVPAHAAKTSPRHVAPASQAAPTEQFVDGIAAIVNKQV
ITLGQLSEKTAQVRGQMQQQRIPVPEDAVLRRQVLQQMINSALQDQEAQKVGIKISDAQL
DQAIGSVAQRNRIGVDQLKREVLASGLSWDQYRSELRSQVQDDALRRRFVEDRITISDSD
VDAFLQSHADMPVGPAAGAPTQPEAAPEPAPVPTGPELVELAQILVEVPDYAASSVVAEK
RKQAETILRKLKSGGNFAGLAAASSNGPQALQGGDMGIRPLKDWPDLFVRAIADVPAGGI
SGIIQSGRGFHILKVVRRGYAQRPAPKKASAPQPAPTPTPARQPAAASGPMMVTQTHARH
ILIKTSKVMSDDKARGILSGLRTRIEHGESFAELAKRYSQDASAPQGGDLGWVNPGDTVP
AFEQAMNALQPDQVSEPVKSPFGWHLIQVEGRRTKNMEQEFRRMQARRELMERRIGPAYE
DWLDQLRSQAYIDNRLEHTRSGTQ