Protein Info for ABCV34_RS09440 in Castellaniella sp019104865 MT123

Annotation: arsenical pump-driving ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 588 TIGR04291: arsenical pump-driving ATPase" amino acids 7 to 571 (565 residues), 904 bits, see alignment E=4.1e-276 PF02374: ArsA_ATPase" amino acids 9 to 291 (283 residues), 191.5 bits, see alignment E=2e-59 amino acids 329 to 461 (133 residues), 98.2 bits, see alignment E=5.2e-31 amino acids 461 to 582 (122 residues), 31.8 bits, see alignment E=8.9e-11 PF01656: CbiA" amino acids 12 to 206 (195 residues), 36.1 bits, see alignment E=5.5e-12 amino acids 330 to 488 (159 residues), 32.3 bits, see alignment E=8.3e-11 TIGR00345: transport-energizing ATPase, TRC40/GET3/ArsA family" amino acids 12 to 292 (281 residues), 275 bits, see alignment E=9.4e-86 PF13614: AAA_31" amino acids 14 to 149 (136 residues), 37.8 bits, see alignment E=1.9e-12

Best Hits

Swiss-Prot: 67% identical to ARSA_ACIMA: Arsenical pump-driving ATPase (arsA) from Acidiphilium multivorum (strain DSM 11245 / JCM 8867 / NBRC 100883 / AIU301)

KEGG orthology group: K01551, arsenite-transporting ATPase [EC: 3.6.3.16] (inferred from 90% identity to rpf:Rpic12D_0650)

Predicted SEED Role

"Arsenical pump-driving ATPase (EC 3.6.3.16)" in subsystem Arsenic resistance (EC 3.6.3.16)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (588 amino acids)

>ABCV34_RS09440 arsenical pump-driving ATPase (Castellaniella sp019104865 MT123)
MHFLTQPPRFLFFTGKGGVGKTSIACATAVQLAAQGQRVLLVSTDPASNVGQVFGEHIGN
RITAITTVPNLWALEIDPQAAAQAYRDRIAGPVRGVLPDDVVRGIEESLSGACTTEIAAF
DEFTALLTDAALVQNYEHVIFDTAPTGHTIRLLQLPGAWSGFLEAGKGDASCLGPLAGLE
KQRSQYKAAVKALADPLRTRLVLVARAQRTALREAARTHEELAAIGLSQQYLVINGVFPA
GETENDALATAIYNREQATLAAIPQGLQALPQDQIALKPFNLVGLEALHQLLVNTDATPD
TNAAELPARLDAPDLSSLVDEIAADGHGLVMVMGKGGVGKTTLAAAIAVELASRGLPVHL
TTSDPAAHLADTLEGSLPDLTLSRIDPEEATARYRQHVMNTKGAQLDAEGRALLEEDLRS
PCTEEIAVFQAFSRAIREGGRKFVVMDTAPTGHTLLLLDATGAYHRDIARQMGETGVHFT
TPMMQLQDPKQTKVLIVTLAETTPVLEAANLQDDLRRAGIEPWAWVVNNSVAAAHPHSSL
LRQRARNELREIEAVATRHARRHAVVPLLTEEPVGVERLRALVNLKVS