Protein Info for ABCV34_RS08900 in Castellaniella sp019104865 MT123

Annotation: arginine/lysine/ornithine decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03709: OKR_DC_1_N
  • amino acids 21 to 145 (125 residues), 115.4 bits, E=3.3e-37
• PF01276: OKR_DC_1
  • amino acids 151 to 584 (434 residues), 498.6 bits, E=2.7e-153
• PF01041: DegT_DnrJ_EryC1
  • amino acids 205 to 285 (81 residues), 20.5 bits, E=5.2e-08
• PF03711: OKR_DC_1_C
  • amino acids 611 to 737 (127 residues), 160.6 bits, E=5e-51

Best Hits

KEGG orthology group: K01584, arginine decarboxylase [EC: 4.1.1.19] (inferred from 88% identity to bbr:BB0850)

Predicted SEED Role

"Arginine decarboxylase (EC 4.1.1.19); Ornithine decarboxylase (EC 4.1.1.17); Lysine decarboxylase (EC 4.1.1.18)" (EC 4.1.1.17, EC 4.1.1.18, EC 4.1.1.19)

MetaCyc Pathways

• superpathway of arginine and polyamine biosynthesis (15/17 steps found)
• superpathway of putrescine biosynthesis (4/4 steps found)
• L-arginine degradation III (arginine decarboxylase/agmatinase pathway) (2/2 steps found)
• putrescine biosynthesis I (2/2 steps found)
• putrescine biosynthesis III (2/2 steps found)
• arginine dependent acid resistance (1/1 steps found)
• cadaverine biosynthesis (1/1 steps found)
• superpathway of polyamine biosynthesis I (6/8 steps found)
• L-lysine degradation X (4/6 steps found)
• L-arginine degradation IV (arginine decarboxylase/agmatine deiminase pathway) (1/3 steps found)
• aminopropylcadaverine biosynthesis (1/3 steps found)
• putrescine biosynthesis II (1/3 steps found)
• superpathway of polyamine biosynthesis II (4/8 steps found)
• spermidine biosynthesis III (1/4 steps found)
• L-lysine degradation I (3/7 steps found)
• bisucaberin biosynthesis (1/5 steps found)
• desferrioxamine B biosynthesis (1/5 steps found)
• desferrioxamine E biosynthesis (1/5 steps found)
• lupanine biosynthesis (1/5 steps found)
• superpathway of ornithine degradation (3/8 steps found)
• superpathway of L-arginine and L-ornithine degradation (6/13 steps found)
• superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation (4/11 steps found)
• superpathway of hyoscyamine (atropine) and scopolamine biosynthesis (4/16 steps found)
• superpathway of L-lysine degradation (10/43 steps found)

KEGG Metabolic Maps

• Alkaloid biosynthesis II
• Arginine and proline metabolism
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Glutathione metabolism
• Lysine degradation
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.17 or 4.1.1.18 or 4.1.1.19

Protein Sequence (754 amino acids)

>ABCV34_RS08900 arginine/lysine/ornithine decarboxylase (Castellaniella sp019104865 MT123)
MKFRFPIVIIDEDYRSENASGFGIRALASAIEAEGVEVLGVTSYGDLSSFAQQQSRASAF
ILSIDDEEFDEDSPEDVANAIKNLRSFIGELRFRNEDIPIYLYGETRTSQHIPNDILREL
HGFIHMFEDTPEFVARHIIREARAYLDSLAPPFFRELLDYASDGSYSWHCPGHSGGVAFL
KSPVGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAESEKNAARIFHADHCFFVTNG
TSTSNKIVWHANVAAGDVVVVDRNCHKSVLHAITMTGAIPVFLRPTRNHLGIIGPIPLEE
FDPENIRRKIEANPFAREAVNKRPRILSLTQSTYDGVIYNVEMIKEKLGSYIDTLHFDEA
WLPHAAFHEFYEDMHAIGPNRPRSHDTMIYATHSTHKLLAGLSQASQIVVQDSETRKLDR
NIFNEAFLMHTSTSPQYAIIASCDVAAAMMEPPGGTALVEESIREALDFRRAMRKVESEF
GKNDWWFKVWGPNRLVPEGIGNREDWILGSGDEWHGFGDLAEGFNMLDPIKATVVTPGLD
ISGTFADSGIPAALVSRYLVEHGVVVEKTGLYSFFILFTIGITKGRWNTLLTALQQFKDD
YDRNQPLWRVLPEFNRAHKRYERMGLRDLCQEIHEAYRHYDFARLTTRVYLSDMVPAMRP
ADAYARMAHREVERVRVEHLEGRVTGVLLTPYPPGIPLLIPGERFNRDIVDYLKFTQEFN
QQFPGFETDVHGLAYETDEQGLRHYYVDCIREQD