Protein Info for ABCV34_RS08420 in Castellaniella sp019104865 MT123

Annotation: Rne/Rng family ribonuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 957 TIGR00757: ribonuclease, Rne/Rng family" amino acids 13 to 423 (411 residues), 517.5 bits, see alignment E=1.3e-159 PF00575: S1" amino acids 36 to 116 (81 residues), 31.1 bits, see alignment E=3.8e-11 PF10150: RNase_E_G" amino acids 120 to 389 (270 residues), 325.9 bits, see alignment E=3.1e-101 PF20833: RNase_E_G_Thio" amino acids 401 to 485 (85 residues), 109.9 bits, see alignment E=8.3e-36

Best Hits

Predicted SEED Role

"Ribonuclease E (EC 3.1.26.12)" in subsystem RNA processing and degradation, bacterial or Ribosome biogenesis bacterial (EC 3.1.26.12)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.26.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (957 amino acids)

>ABCV34_RS08420 Rne/Rng family ribonuclease (Castellaniella sp019104865 MT123)
MKRMLFNATHQEELRVAIVDGQKLIDLDIETAGREQRKGNIYKGVITRIEPGLEACFVSY
GEERHGFLPFKEVARSYFKDGVDVRTARIQDALTEGQELIIQVEKEERGNKGAALTTFIS
LAGRYLVLMPNNPRGGGVSRRVEGEDRQELRDTMDQLEIPSGMSMIARTAGIGRSVEELQ
WDLNYLMQLWTAIDGAAKENKAPILIYLESSLVIRAIRDYFSPEIGEILIDTDDIHDQAT
AFMSVVMPDNVNRVKRYRDDVPLFSRFQIEHQIETAYSRTVTLPSGGAIVIDHTEALVAV
DVNSARSTRGADIEETALRTNVEAADEVARQLRLRDLGGLIVIDFIDMEETKNQRAVETR
LRDALHFDRARVQMGKISRFGLMELSRQRLRPALNEGSHVTCPRCTGTGVIRDAESSALH
VLRLLQEEAMKEGTAALHAQVPVDVATFLLNEKRRDISQIESRLKVNLVLIPNKSLETPH
HHIERLRHDDPRLDENKTSFELVQEPEEKLIWQPNKAQETKARPEALVKGIQPAEPAPPH
VERPTKATVPEASPVATPATGTSGGLIKRILGWLTGTAPSTVQTQETPAAQATPARHEDG
RRRNGAGRNGRRPDQRSGGRTERPARAEKSEQPERGERQERPADSRGGSRRERPAEERAA
QQTAKPVVGDEAPQDTTEPRRNRNRRGRGRAHGEDTQDQAGIEAVALTAAASEALPVSEP
TPAPQAPRVALEPIDDDLLEDTTVAGPAVDVDTDGSLDTPDPERKRRRRRGRRGRRGTEA
GESLSAEGQDMTSEQDADIETHETPRFDPEALDAQAQALAHAEETPQAREQSDQPAPTVT
IHEQAPAPALQAELPPEEVKAEALPETAEEPAPAAQATAAASHTPAPAVTVQDRGTHPIV
LPPIDESLQAAGMQMVETRASSASSYTPPATPKPLGRARKTVTKEQDEPLQQVETTH