Protein Info for ABCV34_RS07435 in Castellaniella sp019104865 MT123

Annotation: pitrilysin family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 915 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF00675: Peptidase_M16" amino acids 53 to 198 (146 residues), 65.4 bits, see alignment E=5.9e-22 PF05193: Peptidase_M16_C" amino acids 206 to 381 (176 residues), 77.9 bits, see alignment E=9e-26 amino acids 665 to 843 (179 residues), 111.8 bits, see alignment E=3.7e-36

Best Hits

KEGG orthology group: K07263, zinc protease [EC: 3.4.24.-] (inferred from 52% identity to put:PT7_1929)

Predicted SEED Role

"putative zinc protease"

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (915 amino acids)

>ABCV34_RS07435 pitrilysin family protein (Castellaniella sp019104865 MT123)
MKRLKSFLSLLVLFLPLAIATPCLAQAKTPPGITPVVMIEGIAEYHLANGLQVLLAPDDS
RAQTTVNMSYKVGSRNEGAGETGMAHLLEHLLFRGSPKHPDALAEFSRRGLAANGSTSTD
LTNYYATFSSNPDTLRWYLSWQADAMLNSRISRADLDAEMPVVRNEMERGENSPFSMLLQ
QTDAAAYVWHPYGRSVIGARSDVEHVDVAQLQAFYHRYYQPDNAVLIVTGRFDTQQVLQW
IAQDFGPMVRPTRVLPPEYTVEPVQQGARATTLRRIGGSPIAIAQYHFPEATSDVFTALS
MGTDMLADTPAGPLYQSLVKSGQASSVFGFARAMQQPGYAVFGAQLQPDADPQAALKILE
QTLESGGIDQLDQTALDRNRTAWLNQWKQIYNQPASLADALSNAVSRGDWRLLFIEPLRV
RALTLDSIRTELKTWLLPSNRTSGLYLPTPDPKYAPAAPAADLKPWIEQLKTGTTRPTVA
TFDTDPQAIDATTQRSALTLPNGTVSMALLPKATPGDQVHGFLRLHFGSVEQMKGLGLVP
SMTAAMLLRGTDDMSRQQIEDRLNALDSELAFNDEGNTLTVSLRSSREHLPELLKLVFHL
LRHPSFPATELAEIQRSLTTNIENEAVSPSYLVRNALQRHGQPWKPEDIRYTPTAQEMLA
QTKTLTRDQLLKFHDRFYGAGGMTVSLVGDFDPKALQDTLRDALSGWHQAPAYVRIPDPW
YAVAPKTFEIPAPGKANANYLATLPLKLQDTDPRWPALMLANYLLGGSEDSRLWQSIRVK
QGLSYGVGSNLRASAFEPSGAWTLFATMASQNAQTLQQAMRATLDATLKSGFTQQDVDQG
VTSLVNYLQLGRSSDTWLADRWLDYLETGRSFAWQQHIIDQLKALKADQVNDAMRTLLKP
DDLSIAVAADSHPKH