Protein Info for ABCV34_RS06865 in Castellaniella sp019104865 MT123

Annotation: cytochrome-c oxidase, cbb3-type subunit II

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details TIGR00781: cytochrome c oxidase, cbb3-type, subunit II" amino acids 10 to 185 (176 residues), 272.3 bits, see alignment E=1.8e-85 PF02433: FixO" amino acids 10 to 191 (182 residues), 264.2 bits, see alignment E=4.4e-83

Best Hits

KEGG orthology group: K00405, cb-type cytochrome c oxidase subunit II [EC: 1.9.3.1] (inferred from 75% identity to put:PT7_1444)

MetaCyc: 66% identical to cbb3-2 cytochrome c oxidase subunit O (Pseudomonas putida KT2440)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoO (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (218 amino acids)

>ABCV34_RS06865 cytochrome-c oxidase, cbb3-type subunit II (Castellaniella sp019104865 MT123)
MSGSKKRFSHEMLERNVGLLIVFSILVVSFSGLVQIIPLFYQHSTTTAVEGVKPYESLRL
VGRDVYIREGCVGCHSQQIRKLQSEVQRYGPYSVAGESVYDHPFLWGSKRTGPDLARVGQ
RYSDEWHRIHLRNPRDVVKESNMPAYPWLQHNTVEGTNVQDRMQVLRTLGVPYTDEDIAT
APEALKGKTEEDALVAFLQGLGVGGRAAAEQAMQNGGR