Protein Info for ABCV34_RS06420 in Castellaniella sp019104865 MT123

Annotation: peptidase U32 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 PF01136: Peptidase_U32" amino acids 96 to 349 (254 residues), 235.5 bits, see alignment E=2.6e-74

Best Hits

Swiss-Prot: 61% identical to YHBU_ECOLI: Uncharacterized protease YhbU (yhbU) from Escherichia coli (strain K12)

KEGG orthology group: K08303, putative protease [EC: 3.4.-.-] (inferred from 83% identity to bpd:BURPS668_2692)

Predicted SEED Role

"FIG139552: Putative protease" in subsystem CBSS-214092.1.peg.3450

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.-.-

Use Curated BLAST to search for 3.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (350 amino acids)

>ABCV34_RS06420 peptidase U32 family protein (Castellaniella sp019104865 MT123)
MSSTPSIRPGVVPHHGLSSFELVCPAGSLPALKSAVDEGADCVYLGFRDATNARNFAGLN
FDATAIAQGIRYAHDRGRKVFLALNTYPQPDAWRLWQESVDRAADSGVDAVIMADPGLMA
YAHARYPDLRLHLSVQGSATNYEAIHFYHERFGIARVVLPRVLSVAQVQQVCENAPVEIE
VFGFGSLCVMVEGRCALSSYATGESPNTHGVCSPAKHVRWQQTDAGLESRLNGVLIDRYD
QGENAGYPTLCKGRFDVAGENYYALEEPTSLNTLELLPKLMAMGVRAIKIEGRQRSPAYV
AQVTRVWRQAIDQARSNSARYSVHPSWMAELNKVAEGQQHTLGAYHRPWK