Protein Info for ABCV34_RS05460 in Castellaniella sp019104865 MT123

Annotation: DEAD/DEAH box helicase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 PF13588: HSDR_N_2" amino acids 53 to 118 (66 residues), 25.5 bits, see alignment E=2.8e-09 PF04851: ResIII" amino acids 160 to 322 (163 residues), 124.9 bits, see alignment E=7.5e-40 PF18766: SWI2_SNF2" amino acids 164 to 359 (196 residues), 55.3 bits, see alignment E=2e-18 PF00270: DEAD" amino acids 164 to 322 (159 residues), 35.1 bits, see alignment E=2.8e-12 PF08463: EcoEI_R_C" amino acids 641 to 799 (159 residues), 106.8 bits, see alignment E=3.2e-34

Best Hits

KEGG orthology group: K01153, type I restriction enzyme, R subunit [EC: 3.1.21.3] (inferred from 79% identity to app:CAP2UW1_3126)

Predicted SEED Role

"Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)" in subsystem Restriction-Modification System (EC 3.1.21.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.3

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (800 amino acids)

>ABCV34_RS05460 DEAD/DEAH box helicase family protein (Castellaniella sp019104865 MT123)
MRDGVITEADTCREFITPRLVEAGWGSAPHTIGEQRSFTNGRILVTGGKVRRGQRKRADY
LLYYRRDYPLAVVEAKEIGLPAETGVQQAREYAEILGLKFAYATNGHRIIEIDYTTGTEH
EVDRYATPDELFARLTAAAQFPQSVSSYLLEPFNLVSGKVPRYYQQIAINRVIEGILLGQ
KRILATLATGTGKTCVAFQICWKLWNSRWNRTGEHRRPKILFLADRNILVDDPMAKMFAP
FGDARHKIAGGDTSQSRDMYFGIYQALTTASADVFRQYRPDFFDLIIIDECHRGSSRDES
AWRAVLDYFEPAVQFGMTATPLREESRNSYEYFGNPVYTYSLRQGIEDGFLAPYRVHRVI
TTVDAAGWRPSKDELDRYGRKVPDEEYQTKDFERVIALRSRTQAMARHLTDLLKGTDRFA
KTLVFCVDQEHAAEMRQELINLNSDLVKQYPDYVCRVTADEGAIGLTHLSHFQDVDKPTP
VILTTSQLLTTGVDAEMVKNVVLARVVGSRSEFKQIVGRGTRLKVDYGKEYFNIIDFTGT
ATQHFADPDFDGDPARIEEIMVDESGEVVETTTDEAPSVAEPEAQYEFETEQDDDSGSNG
EIITEPPTEPRKFYIDGGEVEVIGHLIYDLDTDGKKLQVVKYTEYSGRAVRTLYPTREAL
QSAWANPDTRAEVLRELTERGISFEELAASSEQPDADPFDLLCHLGWNAPLLTRRQRAEA
AKRQAQDLFTQHGETAREILSLLLDRYVERGILQFNALSELMKVQPFDRYGSPSEIATRH
FGGVRGMKDAVSRLQTALYQ