Protein Info for ABCV34_RS05140 in Castellaniella sp019104865 MT123

Annotation: trigger factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 436 PF05697: Trigger_N" amino acids 1 to 143 (143 residues), 128.2 bits, see alignment E=4.7e-41 TIGR00115: trigger factor" amino acids 11 to 417 (407 residues), 429.2 bits, see alignment E=7.5e-133 PF00254: FKBP_C" amino acids 158 to 239 (82 residues), 56 bits, see alignment E=6.3e-19 PF05698: Trigger_C" amino acids 265 to 417 (153 residues), 120.2 bits, see alignment E=1.4e-38

Best Hits

Swiss-Prot: 73% identical to TIG_BORPD: Trigger factor (tig) from Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)

KEGG orthology group: K03545, trigger factor (inferred from 75% identity to put:PT7_0728)

MetaCyc: 38% identical to trigger factor (Escherichia coli K-12 substr. MG1655)
Peptidylprolyl isomerase. [EC: 5.2.1.8]

Predicted SEED Role

"Cell division trigger factor (EC 5.2.1.8)" in subsystem Bacterial Cell Division (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (436 amino acids)

>ABCV34_RS05140 trigger factor (Castellaniella sp019104865 MT123)
MQPVVEKLSGLERRVDLTVSVADIEKEVQAQLKRVARTAKVHGFRPGKAPLSVIERSHGP
SVRYDVINSQIGKSLDKVIADANLRVAGSPNLEPKTEGGDDGVMAFSATFEVYPEVALPD
LSSLKITRSTAQVGDAEVQKTIDILRRQRTVFKPAADRAAQDGDRVTLDFAGTIDGVAFD
GGTAQDFPFVLGQGRMLPEFEAAATGLKAGESKTFPLDFPADYGSAAVAGKQAEFTITVK
EVAEPELPEMDADFAKSLGQAEGNVEALLADVRGNVEREAQARARNRTKASVMDALAAAC
SFDLPKALVDDEVANRTAAAREELKQRGLPNADSIPIPEDTFRPEAERRVRLGLLVGELI
KAADLKAKPEQVRARIEDFAKSYEQPAQVVAYYLSDRQRRAEIESLVLEDNVVDHVLAAA
QVTDEAVDFDTLMGTR