Protein Info for ABCV34_RS03945 in Castellaniella sp019104865 MT123

Annotation: sulfate ABC transporter permease subunit CysW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 295 transmembrane" amino acids 26 to 48 (23 residues), see Phobius details amino acids 72 to 97 (26 residues), see Phobius details amino acids 108 to 133 (26 residues), see Phobius details amino acids 145 to 168 (24 residues), see Phobius details amino acids 209 to 232 (24 residues), see Phobius details amino acids 253 to 274 (22 residues), see Phobius details TIGR02140: sulfate ABC transporter, permease protein CysW" amino acids 24 to 282 (259 residues), 414 bits, see alignment E=2.6e-128 TIGR00969: sulfate ABC transporter, permease protein" amino acids 28 to 281 (254 residues), 332 bits, see alignment E=2.9e-103 PF00528: BPD_transp_1" amino acids 89 to 274 (186 residues), 44.5 bits, see alignment E=7.5e-16

Best Hits

Swiss-Prot: 56% identical to CYSW_ECOLI: Sulfate transport system permease protein CysW (cysW) from Escherichia coli (strain K12)

KEGG orthology group: K02047, sulfate transport system permease protein (inferred from 73% identity to nmu:Nmul_A0504)

MetaCyc: 56% identical to sulfate/thiosulfate ABC transporter inner membrane subunit CysW (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate transport system permease protein CysW" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (295 amino acids)

>ABCV34_RS03945 sulfate ABC transporter permease subunit CysW (Castellaniella sp019104865 MT123)
MASIALDPILSAGAARLNDEGRYVRLALMGVAFSFLFLFLFIPLLAVFHQALAKGWAVCL
AAVTDPDALAAIRLTLTAAAIAVPLNLVFGVCAAWAVARFEFRGKSLLLTLIDLPFSVSP
VIAGLTYVLLFGAQGWFGPWLQAHGIQILFAVPGIVLATVFVTVPFVARELIPLMQSQGS
DEEEAALVLGASGWRVFWHVTLPNIRWGLFYGVILCNARAMGEFGAVSVVSGHIRGQTNT
LPLHVEILYNEYHFAAAFSVASLLALLALLTLALKSLAEWRLRTQAEKAASELSS