Protein Info for ABCV34_RS02690 in Castellaniella sp019104865 MT123

Annotation: DNA primase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 630 TIGR01391: DNA primase" amino acids 1 to 415 (415 residues), 452.1 bits, see alignment E=8.9e-140 PF01807: zf-CHC2" amino acids 3 to 97 (95 residues), 122.6 bits, see alignment E=2e-39 PF08275: DNAG_N" amino acids 128 to 249 (122 residues), 124.4 bits, see alignment E=1.2e-39 PF13662: Toprim_4" amino acids 257 to 323 (67 residues), 54 bits, see alignment E=6.3e-18 PF13362: Toprim_3" amino acids 258 to 351 (94 residues), 27.3 bits, see alignment E=1.7e-09 PF01751: Toprim" amino acids 258 to 327 (70 residues), 49.1 bits, see alignment E=2.1e-16 PF13155: Toprim_2" amino acids 260 to 346 (87 residues), 60.3 bits, see alignment E=7.9e-20 PF10410: DnaB_bind" amino acids 366 to 420 (55 residues), 42.5 bits, see alignment 2.4e-14 PF08278: DnaG_DnaB_bind" amino acids 498 to 618 (121 residues), 61.8 bits, see alignment E=3.5e-20

Best Hits

KEGG orthology group: K02316, DNA primase [EC: 2.7.7.-] (inferred from 64% identity to put:PT7_1387)

Predicted SEED Role

"DNA primase (EC 2.7.7.-)" in subsystem DNA-replication or Macromolecular synthesis operon (EC 2.7.7.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.-

Use Curated BLAST to search for 2.7.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (630 amino acids)

>ABCV34_RS02690 DNA primase (Castellaniella sp019104865 MT123)
MIPESFIQELLARVDIVDVVGRYVQLRKGGANLLGLCPFHTEKTPSFTVSPTKQFYHCFG
CGAHGSAIHFLTEHTGAPFPEAVRSLAASVGMTVPEEPRSPRQRAAERERREEGSRQRDI
LRQAQAHYRAALKQAPQAIAYLKKRGLSGEIAARYGLGWAGADRRGLASVFEHYEDPSLI
ESGLVVESEDGRRHDRFRGRVMFPIHDGRGQLIGFGGRLIEPGEPKYLNSPETSLFSKGN
ELYGLHEARAGIRAEGCVLVVEGYMDVVALAQFGLGNAVATLGTSTTATHIQKLCRASDR
IIFSFDGDGAGRKAAWRALQACLPWVAEDVSMRFLFLPEGQDPDSYVRAYGVQALRAYLD
EALPLSRFLLEELGTRHDLREAEGRAACVHEARPLFAQMPDGGFRLQVEREFAQQVRLTP
DELSRMLSAGPVVAPSGTPGTQPPGASVGSKPRAPASDEPPWLADGSGHAPSEASTVSPS
GSRRGRRGGARTVTPLARRLLRLLLAHPALVDGLGDQQLELLAHHPHLILVRELIGLACA
CGGRHAGALLEAAEPGSDLAQAIRDLSTEVMMQELPDPEAEWRDALRHIELQAVQEQCDR
LIDAGIDSETQRRRYQDLSRQLARLKAGAG