Protein Info for ABCV34_RS02185 in Castellaniella sp019104865 MT123
Annotation: transporter substrate-binding domain-containing protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 43% identical to HISJ_ECOL6: Histidine-binding periplasmic protein (hisJ) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
KEGG orthology group: K10013, lysine/arginine/ornithine transport system substrate-binding protein (inferred from 52% identity to bpl:BURPS1106A_2777)Predicted SEED Role
"Lysine-arginine-ornithine-binding periplasmic protein precursor (TC 3.A.1.3.1)" in subsystem Arginine and Ornithine Degradation (TC 3.A.1.3.1)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (263 amino acids)
>ABCV34_RS02185 transporter substrate-binding domain-containing protein (Castellaniella sp019104865 MT123) MKTTLLGAALLIAAGFIPAIGSAADAPELKIATEAGYPPFEYRNPSGQLEGFDIDIGNEL CKRLQRTCVWIDQSFDSLIPGLQARKFDLANSTMTATEARKKVIDFSTPMYIVPVKLLVK KGSGLEPTAESLKGKRVGVQQGTTMETYARKHWAPKEVQVIAYPSYTNAYVDMKAGRLDA TFQEAQSAVDGFLSKPEGAGYELASMTLKDPILNEPIAMGMRKGNTKLGTEVDKTLKAML ADGTIQGFAKKYFAKDLIQFPAQ