Protein Info for ABCV34_RS01550 in Castellaniella sp019104865 MT123

Annotation: isochorismatase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00857: Isochorismatase
  • amino acids 36 to 217 (182 residues), 96.5 bits, E=1e-31

Best Hits

Swiss-Prot: 48% identical to CSH_ARTSP: N-carbamoylsarcosine amidase from Arthrobacter sp.

KEGG orthology group: None (inferred from 73% identity to xau:Xaut_0856)

MetaCyc: 48% identical to N-carbamoylsarcosine amidohydrolase subunit (Arthrobacter sp.)
N-carbamoylsarcosine amidase. [EC: 3.5.1.59]

Predicted SEED Role

"N-carbamoylsarcosine amidase (EC 3.5.1.59)" (EC 3.5.1.59)

MetaCyc Pathways

• creatinine degradation II (3/5 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.59

Use Curated BLAST to search for 3.5.1.59

Protein Sequence (238 amino acids)

>ABCV34_RS01550 isochorismatase family protein (Castellaniella sp019104865 MT123)
MSDNLEQVLEAAFAEATRRYQSRGFQRRVGFGKRPALISVDLANAWTRPGNPFTCEHVDD
QIIPSMQALLKGFRKYNLPVVHVTTCYEITDRDNQNTDMGLWHNKIPIDVVSQGNPDIWA
IDSRIAPIEGELTLIKKRASAFHGTYLAGYLRAAGVDTILVTGVTASACVRETICDGLAD
GFRTIAVKEAIGDRVPGAVLWNLFDIDAKFGDVETTETCLKYLDRIGQEQEVPEKAVA