Protein Info for ABCV34_RS01345 in Castellaniella sp019104865 MT123
Annotation: histidine phosphatase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K08296, phosphohistidine phosphatase [EC: 3.1.3.-] (inferred from 51% identity to sme:SMc03822)Predicted SEED Role
"Phosphohistidine phosphatase SixA"
KEGG Metabolic Maps
- Aminosugars metabolism
- Ascorbate and aldarate metabolism
- Ether lipid metabolism
- Fructose and mannose metabolism
- Lipopolysaccharide biosynthesis
- Nicotinate and nicotinamide metabolism
- Riboflavin metabolism
- Sphingolipid metabolism
- Thiamine metabolism
Isozymes
Compare fitness of predicted isozymes for: 3.1.3.-
Use Curated BLAST to search for 3.1.3.-
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (170 amino acids)
>ABCV34_RS01345 histidine phosphatase family protein (Castellaniella sp019104865 MT123) MLLRHAKSDWPTGVDDHERPLRAGRGRQASALMGKYMAREGLAPDLVIVSTARRAQETWD LACSAFAQPIPRRNDPRLYEATAGSLLQVVHETRDDIHTLLLVGHHPGFQSLALELSRDA SGPVATRVRDKYPTAGLAVIDFDVAHWNQVRPATGKIRRFETPRLIDSGN