Protein Info for ABCV34_RS00105 in Castellaniella sp019104865 MT123

Annotation: organomercurial transporter MerC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 141 transmembrane" amino acids 12 to 41 (30 residues), see Phobius details amino acids 48 to 70 (23 residues), see Phobius details amino acids 78 to 98 (21 residues), see Phobius details amino acids 104 to 122 (19 residues), see Phobius details PF03203: MerC" amino acids 9 to 121 (113 residues), 83.3 bits, see alignment E=9.2e-28

Best Hits

KEGG orthology group: None (inferred from 77% identity to aby:ABAYE3604)

Predicted SEED Role

"Mercuric transport protein, MerC" in subsystem Mercury resistance operon

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (141 amino acids)

>ABCV34_RS00105 organomercurial transporter MerC (Castellaniella sp019104865 MT123)
MGLMTRIADKTGALGSVVSAMGCAACFPALASFGAAIGLGFLSQYEGLFITTLLPLFAAL
ALLASILGWLSHRQWLRAALGAIGPLLVLLAALLMRFYGLPTAPLLYVGLTFMVGVSIWD
FVSPAHRRCGSDGCELPPQRG