Protein Info for ABCV34_RS00070 in Castellaniella sp019104865 MT123

Annotation: Hg(II)-responsive transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 142 TIGR02051: Hg(II)-responsive transcriptional regulator" amino acids 9 to 132 (124 residues), 184 bits, see alignment E=5.8e-59 PF13411: MerR_1" amino acids 9 to 75 (67 residues), 62.3 bits, see alignment E=5.6e-21 PF00376: MerR" amino acids 9 to 46 (38 residues), 44.9 bits, see alignment E=1.3e-15 PF09278: MerR-DNA-bind" amino acids 51 to 113 (63 residues), 67.3 bits, see alignment E=2.2e-22

Best Hits

Swiss-Prot: 92% identical to MERR_SERMA: Mercuric resistance operon regulatory protein (merR) from Serratia marcescens

KEGG orthology group: None (inferred from 91% identity to adk:Alide2_3381)

Predicted SEED Role

"Mercuric resistance operon regulatory protein" in subsystem Mercury resistance operon

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (142 amino acids)

>ABCV34_RS00070 Hg(II)-responsive transcriptional regulator (Castellaniella sp019104865 MT123)
MQTIFENLTIGVFAKAAGVNVETIRFYQRKGLLPQPDKPYGSIRRYGEADVTRVRFVKSA
QRLGFSLDEIAELLRLDDGTHCDEASHLAEHKLQDVREKMADLVRMETVLSELVCACHAR
NGNVSCPLIASLQENRTVLTTP