Protein Info for DvMF_2736 in Desulfovibrio vulgaris Miyazaki F

Annotation: type II secretion system protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 transmembrane" amino acids 6 to 29 (24 residues), see Phobius details amino acids 111 to 135 (25 residues), see Phobius details amino acids 141 to 162 (22 residues), see Phobius details amino acids 293 to 315 (23 residues), see Phobius details PF00482: T2SSF" amino acids 182 to 310 (129 residues), 78.1 bits, see alignment E=3e-26

Best Hits

KEGG orthology group: K12511, tight adherence protein C (inferred from 100% identity to dvm:DvMF_2736)

Predicted SEED Role

"Type II/IV secretion system protein TadC, associated with Flp pilus assembly" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DJ14 at UniProt or InterPro

Protein Sequence (326 amino acids)

>DvMF_2736 type II secretion system protein (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MPFDETMIPFLAALLASGAVLLVAQALRGMFGNRQRVQRMHGRLTRHAAGARAVAVAAPA
LPESPLSSLKAALNAVAERVGQRVVKDDGEEVNEAGLALVRAGYRNRRAPLVFWGVKAGL
TLCGLLLGLVVRLLAGNDIPLGMVALLFICPAVVGLYAPNVWLSRRIKARRLDIINSLPD
ALDLLVVCVEAGMGLDQAFSRVAREMAATNPVLAEELNLVILELRAGKSRAEALKNLAAR
VALEDVNSLVTLIVQADAFGTSISSTLRVYSDTMRTTRFQRAEEIAAKMPVKLLFPLVFC
ILPALFVTIMGPAFIKLMQVFAQMGQ