Protein Info for DvMF_2678 in Desulfovibrio vulgaris Miyazaki F

Annotation: PAS/PAC sensor signal transduction histidine kinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 698 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13188: PAS_8" amino acids 290 to 341 (52 residues), 15.6 bits, see alignment 2.5e-06 PF00512: HisKA" amino acids 421 to 485 (65 residues), 31.4 bits, see alignment E=3.2e-11 PF02518: HATPase_c" amino acids 615 to 687 (73 residues), 42.3 bits, see alignment E=1.9e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_2678)

Predicted SEED Role

"sensory box histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DIV6 at UniProt or InterPro

Protein Sequence (698 amino acids)

>DvMF_2678 PAS/PAC sensor signal transduction histidine kinase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MRLPRRLPSPVAALLSQIADVPGVPYAPPDPFSPPASAPPPGVAGGRIHPSPPDVAPMGG
FSYAASVILPQTGWHASEFLPRLVGELSSPGNLSVLEREMHRQATGAPTPYSLALRGETG
TPVELLVTPRPLRGVATGTEGEGPVLCATLTATPLPSQSSEGPAPAWSERTRLLNLLDRL
PAYVVLLGPDYSIRYENRGFRQLFGPGVGRPCYEVIRGHSQPCALCPPFDVFDSRTLCVC
EWACPDRRSAFRIYSYPFEDVDGSPLVLKLGIDITSGVRAQEALSISEGRYRSITDNLTL
GIAVLDRALGITASNPRLREWFGDAAAPGGLLCRMLAEHCGEDNTRCPGCACLATFRDGQ
THEWRLETTARSGGRRSYRLTSCPILAGDGGVDSVIVMLEDETDRLRVEERLQRARKLEA
MGTLATGIAHEINQPLSALQLYAGSLEMLAEKDRAPDRETLLARLSLILGETARIRDIID
HMRALVAHGDTALSPTQVEAAVDRALGLVGAQLRAHQVTVDRALPPDLPAVRANPVQLEQ
VVINLVVNAMHALDAREPAGGQDRRIRIEAAYRPAPRGGAERPELPDRPDRPDRAERPEH
GDGQGACPADGEAPAGRVLLTVVDNGPGLQGLEDRVFDPFFTTKGPHKGLGLGLAIVHSF
VESWGGEISVSGGEPPMTGAAFTLALRRASPPESGSDG