Protein Info for DvMF_2617 in Desulfovibrio vulgaris Miyazaki F

Annotation: nitrogenase molybdenum-iron protein beta chain (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 458 TIGR01286: nitrogenase molybdenum-iron protein beta chain" amino acids 12 to 451 (440 residues), 444.7 bits, see alignment E=2e-137 PF00148: Oxidored_nitro" amino acids 24 to 441 (418 residues), 433.9 bits, see alignment E=2.7e-134

Best Hits

Swiss-Prot: 59% identical to NIFK_CLOPA: Nitrogenase molybdenum-iron protein beta chain (nifK) from Clostridium pasteurianum

KEGG orthology group: K02591, nitrogenase molybdenum-iron protein beta chain [EC: 1.18.6.1] (inferred from 100% identity to dvm:DvMF_2617)

MetaCyc: 59% identical to [MoFe]-nitrogenase complex nitrogenase component beta subunit (Clostridium pasteurianum)
Nitrogenase. [EC: 1.18.6.1]

Predicted SEED Role

"Nitrogenase (molybdenum-iron) beta chain (EC 1.18.6.1)" in subsystem Nitrogen fixation (EC 1.18.6.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.18.6.1

Use Curated BLAST to search for 1.18.6.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DR78 at UniProt or InterPro

Protein Sequence (458 amino acids)

>DvMF_2617 nitrogenase molybdenum-iron protein beta chain (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MLLRHTPTEIKERSALNINPAKTCQPIGAMYAGLGIKGCLPHSHGSQGCCAYHRSTLTRH
YKEPVSAATSSFTEGASVFGGQANLLQAIENIFSVYEPEIIAVHTTCLSETIGDDLNQIV
DKAVKEGKVPDGKQVIFASTPSYVGSHVTGFSNMVKGMVKCLAVSSGKKNGKVNIIPGWV
EPADMEEIKRIAGMIGVSFTMFPDTSGVLNGPLTGEYHMFPDAGTPAEDIRAAGDAIGTL
ALGEWCSADAARTLDSQCKVPCRVLDMPIGLKATDRFIDALRVVAGTSVPDTVNFERGQL
IDVISDYHQYFFGKKVALVGDPDQLIALTEFLLTLDMQPVHVVTGTPGKKFEARIRELCA
GKGFDVNVRAAGDMFLLHQWIKNEPVDLIMGNTYCKYIVRDEDIPYVRFGFPIMDRVGHQ
YFPVTGYKGGIRLMEKILGVLLDRADRDAPEEKFELVY