Protein Info for DvMF_2380 in Desulfovibrio vulgaris Miyazaki F

Annotation: NUDIX hydrolase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 169 PF00293: NUDIX" amino acids 31 to 150 (120 residues), 69.1 bits, see alignment E=3.9e-23 PF14815: NUDIX_4" amino acids 34 to 148 (115 residues), 70.9 bits, see alignment E=8.1e-24

Best Hits

KEGG orthology group: K03574, 7,8-dihydro-8-oxoguanine triphosphatase [EC: 3.6.1.-] (inferred from 100% identity to dvm:DvMF_2380)

Predicted SEED Role

"Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (EC 3.6.1.-)" in subsystem Nudix proteins (nucleoside triphosphate hydrolases) (EC 3.6.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.-

Use Curated BLAST to search for 3.6.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DIM3 at UniProt or InterPro

Protein Sequence (169 amino acids)

>DvMF_2380 NUDIX hydrolase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MAAGCIPAEGADTPATGLASDPTPSPARRIAVVAGILWDGERFLAVERPEGKPQAGFWEF
PGGKIEPGEAPADALTRELREELGVTPVQATFWRTVRHDYPHLSVELHFFHVTGFTGTVT
ALEGHRFAWLTWDEAMRLPFLEADLPLVADLRDGPGTGQGTGQGQDTDG