Protein Info for DvMF_2372 in Desulfovibrio vulgaris Miyazaki F

Name: prfC
Annotation: peptide chain release factor 3 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 529 TIGR00503: peptide chain release factor 3" amino acids 6 to 527 (522 residues), 785.3 bits, see alignment E=2.5e-240 PF00009: GTP_EFTU" amino acids 11 to 275 (265 residues), 175.6 bits, see alignment E=1.7e-55 TIGR00231: small GTP-binding protein domain" amino acids 15 to 152 (138 residues), 77.7 bits, see alignment E=8.5e-26 PF01926: MMR_HSR1" amino acids 15 to 142 (128 residues), 24.3 bits, see alignment E=5.9e-09 PF03144: GTP_EFTU_D2" amino acids 312 to 378 (67 residues), 43 bits, see alignment E=9.8e-15 PF16658: RF3_C" amino acids 386 to 513 (128 residues), 155.7 bits, see alignment E=1.2e-49

Best Hits

Swiss-Prot: 100% identical to RF3_DESVM: Peptide chain release factor 3 (prfC) from Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637)

KEGG orthology group: K02837, peptide chain release factor 3 (inferred from 100% identity to dvm:DvMF_2372)

Predicted SEED Role

"Peptide chain release factor 3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DIL5 at UniProt or InterPro

Protein Sequence (529 amino acids)

>DvMF_2372 peptide chain release factor 3 (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MSSRLEREAARRRTFAIISHPDAGKTTLTEKLLLFGGAIQMAGSVKARKAARHATSDWMA
MERERGISVTTSVMQFPYRDRVVNLLDTPGHQDFSEDTYRVLTAVDSALVVIDAAKGVEA
QTRKLMDVCRMRATPVMTFVNKMDREALHPLDVMADIEQHLQIECAPMTWPIGMGSSFKG
TYDLLHKQLHLFSATHGGRIQSGIVIHGADDPQLDEYLGDQAEQLRMDLALLEEAGTPFD
EERYLKGELTPVFFGSAINNFGVREMLDMFVEFAPGPQPRPAATRVVEPGEEAFTGVVFK
IQANMDKAHRDRMAFLRICSGTFTRGMRLKHHRTGKDVTVANATIFMAQDRTGVEEAFPG
DIIGIPNHGTIKIGDTFTESKEVLKFVGIPNFAPEHFRRVRLKNPLKAKQLQKGLEQLAE
EGAVQLFRPLVNNDYILGAVGVLQFDVIVARLADEYGVDAVYEGVSTHTARWVYCEDKKI
FADFQDYHRGELAVDAEGALAYLAPNPWRLESAMERYPKVEFRTTREIS