Protein Info for DvMF_2363 in Desulfovibrio vulgaris Miyazaki F

Annotation: protein TolR (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 139 transmembrane" amino acids 17 to 38 (22 residues), see Phobius details TIGR02801: protein TolR" amino acids 12 to 131 (120 residues), 128 bits, see alignment E=1.7e-41 PF02472: ExbD" amino acids 13 to 132 (120 residues), 106.3 bits, see alignment E=6.1e-35

Best Hits

Swiss-Prot: 42% identical to EXBD_ECOL6: Biopolymer transport protein ExbD (exbD) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K03559, biopolymer transport protein ExbD (inferred from 100% identity to dvm:DvMF_2363)

MetaCyc: 42% identical to Ton complex subunit ExbD (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Biopolymer transport protein ExbD/TolR" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DIK6 at UniProt or InterPro

Protein Sequence (139 amino acids)

>DvMF_2363 protein TolR (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MGASVGNKGGFVAEINVTPFVDVMLVLLIIFMVTAPMMTEGLEVDLPQTRTVQVLPADSD
HLLLTVRKDGVMYLDEYKVTIEELEGYLQRLVKEKNKLLFLQADKAVPYGVVVDVMGHIK
AAGIEKLGVVAEREDPKKK