Protein Info for DvMF_2353 in Desulfovibrio vulgaris Miyazaki F

Annotation: FAD linked oxidase domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1204 transmembrane" amino acids 931 to 937 (7 residues), see Phobius details PF01565: FAD_binding_4" amino acids 139 to 277 (139 residues), 123.9 bits, see alignment E=1.8e-39 PF02913: FAD-oxidase_C" amino acids 393 to 506 (114 residues), 39.6 bits, see alignment E=2.3e-13 amino acids 561 to 686 (126 residues), 85 bits, see alignment E=3.2e-27 PF13237: Fer4_10" amino acids 723 to 801 (79 residues), 29.7 bits, see alignment 2.2e-10 PF13183: Fer4_8" amino acids 725 to 804 (80 residues), 47.8 bits, see alignment 7.7e-16 PF12838: Fer4_7" amino acids 728 to 804 (77 residues), 32.2 bits, see alignment 5.3e-11 PF13534: Fer4_17" amino acids 728 to 805 (78 residues), 26.2 bits, see alignment 4.2e-09 PF13187: Fer4_9" amino acids 728 to 803 (76 residues), 28 bits, see alignment 8e-10 PF00037: Fer4" amino acids 787 to 803 (17 residues), 21.4 bits, see alignment (E = 7.5e-08) PF02754: CCG" amino acids 920 to 1008 (89 residues), 27.5 bits, see alignment 1.2e-09 amino acids 1060 to 1150 (91 residues), 25.2 bits, see alignment 6.3e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_2353)

Predicted SEED Role

"oxidoreductase, FAD/iron-sulfur cluster-binding domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DIJ6 at UniProt or InterPro

Protein Sequence (1204 amino acids)

>DvMF_2353 FAD linked oxidase domain protein (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MPHKGPHISISADFVVNRILRINLDEFEDWPESVRHLAIEIAEELFLVVYNPFIDAETVK
ASVRARFEGEKAALAHHYATSIGEGITMFWSAHEAEVAYRDELVKRMAAVMPRECIDTRP
GALVENSTDATDLRMELPMLVVSPASAEQVSAVVKLANELKFAIIPRGGGSGLTGGAVPA
RKRTVILSLGRLTRIVSIDEQNRVLCCEAGVITNDAIVAAGKKGLLFTVDPASKLASSIG
GNIAENAGGPFAFEYGTTLDNLLSWRMVTPTGEIIDVARVNHPRHKIMPGETATFEIRDL
SGGVRNVVSLRGDEIRLPGLGKDVTNKTLGGLPGMQKEGVDGIIVEACFVLHKKPTHQRV
LVLEFFGRSMNSAMQVIKDVVGYRDTIRREGDHVKISALEEFNSKYVKAIEYKKKSTDYE
GDPISVLIVQLDGDDEFHLDRAVHQILDIVNPYDGADIFAARDEKEAEVFWEDRHKLSAI
ARRTSGFKINEDVVIPIDGVPEFADFLEQVNLECAAAAYRSALQEVGRLAGMPLDDREFN
REFTYASKVAKGEVSAKDISDEEMQIRAVVFLGELANAHPNLARKIERIKDHMQATRIEV
ASHMHAGDGNCHVNIPVNSNDPVMLHNAEQVAHRVMAKAQEVGGEVSGEHGIGITKIAFL
RKEKMDALRAFKERVDPRNVLNPAKLTQRELPVRPFTFSFNRLIEDIRQSGLPDKERLIA
LLANVQICTRCGKCKQVCPMFYPEQSLQYHPRNKNIALGALVEAVYYSQVNKGRPDPFLL
GELRTMMEHCTGCGRCTSVCPVKIDSSGVALAMRAFLESENAGGHPIKRKVLEWLSADPA
SRVPRAAKAASMGQRFQNRFVGLVPAGWRERFESPLFAGPGPEVGYKNLAETLHLGKGGI
FVPASARERARQQGTPVEAVFYFPGCGAGLFYRNIGLAGLMLMLKSGVAVVMPEQHLCCG
YPLLSAGADNAFATNRDRNVQAIRAALDKARAAGLDVTHVITACGSCRDGIQRHELLGTQ
GTAPTRHMDMVQFLLERLPPNTLSADALSGTAKPAAGTEVLYHPSCHAEWVGVHKGKAAN
LYAQAVAAFTGAKVRVNPGCCGESGMGAMTSPAIYNKLRARKRMRLEADFMTYADGAPVI
VGCPSCKVGIKRTMLALKDKRPVLHTLEWLAELAKGADWRKILRKAADQAKDEGGVRVVD
DSGL